Senior LVV Downstream Engineer: Scale-Up & Modeling
Legend Biotech US
Stand out for this role — generate a tailored resume and cover letter in about a minute.
Benefits offered by this job
Job summary
Legend Biotech US is seeking a Senior Engineer / Principal Engineer for Lentivirus Downstream Process Development in Somerset, NJ. The role focuses on designing, optimizing, and scaling purification processes for LVV, integrating analytics, and enabling GMP manufacturing.
Strong modeling and data analytics skills are required to drive scalable solutions. The candidate will lead cross‑functional collaborations, contribute to process transfer, and help shape development strategies for CAR‑T and
Qualifications
- PhD or MS with biotech process development experience.
- Strong background in purification, chromatography, and TFF.
- Experience with LVV or viral vectors preferred.
- GMP/CMC knowledge for clinical development.
Responsibilities
- Design, optimize, and scale LVV downstream purification processes.
- Build mechanistic and hybrid models to influence process development.
- Lead tech transfer from bench to GMP manufacturing and support regulatory submissions.
- Collaborate cross‑functionally to maximize vector recovery and purity.
Skills
Education
Tools
Job description
Legend Biotech US is seeking a Senior Engineer / Principal Engineer for Lentivirus Downstream Process Development in Somerset, NJ. The role focuses on designing, optimizing, and scaling purification processes for LVV, integrating analytics, and enabling GMP manufacturing.
Strong modeling and data analytics skills are required to drive scalable solutions. The candidate will lead cross‑functional collaborations, contribute to process transfer, and help shape development strategies for CAR‑T and
'/%3e%3cpath%20d='M101.744%2012.4726L102.894%2016.1947L99.0021%2013.2201L101.744%2012.4726ZM105.3%208.40937H100.488L99.0026%203.59473L97.5116%208.41047L92.7%208.40385L96.5965%2011.3834L95.1055%2016.1942L99.0021%2013.2196L101.408%2011.3834L105.3%208.40992V8.40937Z'%20fill='white'/%3e%3cdefs%3e%3clinearGradient%20id='paint0_linear_5593_1381'%20x1='90'%20y1='9.44471'%20x2='99'%20y2='9.44471'%20gradientUnits='userSpaceOnUse'%3e%3cstop%20stop-color='%2300AD70'/%3e%3cstop%20offset='0.998594'%20stop-color='%2300B67A'/%3e%3cstop%20offset='1'%20stop-color='%23DCDCE6'/%3e%3c/linearGradient%3e%3c/defs%3e%3c/svg%3e){kind=small}
