Senior LNP Formulation Scientist, Targeted Delivery

Sendabiosciences; Cambridge (MA); On-site; USD 70,000 - 105,000; Full time

Job summary

Sail Biomedicines is seeking a Senior Research Associate to join the Targeted Drug Delivery team. This onsite, lab-based role supports the development of targeted lipid nanoparticle formulations for nucleic acid delivery.

The role requires hands-on experiments, collaboration with cross-functional teams, and meticulous data recording to advance Sail’s delivery platform. 1–3+ years in related fields is preferred.

Qualifications

• Bachelor’s or Master’s degree in Pharmaceutical Sciences, Chemical Engineering, Bioengineering, Biochemistry, Molecular Biology, Chemistry, or a related field.
• 1–3+ years of relevant laboratory experience, industry preferred.
• Hands-on nanoparticle formulation, bioconjugation, or related areas preferred.
• Foundational understanding of lipid nanoparticle systems and nucleic acid delivery.
• Strong organizational, written and verbal communication skills.

Responsibilities

• Formulate, optimize, and evaluate targeted nanoparticle (TNP) formulations for nucleic acid delivery.
• Prepare TNP batches for in vitro and in vivo studies.
• Assess transfection efficiency, potency, and stability of formulations.
• Characterize nanoparticles and conjugates (DLS, Zeta potential, UV-Vis, SDS-PAGE, LC/MS).
• Collaborate with biology, analytics, and computation teams to advance platforms.

Skills

Nanoparticle formulation

Bioconjugation

Analytical characterization

Experimental design

Data analysis

Cross-functional collaboration

Education

Bachelor’s or Master’s degree in Pharmaceutical Sciences, Chemical Engineering, Bioengineering, Biochemistry, Molecular Biology, Chemistry, or related field

Tools

DLS

Zeta potential

UV-Vis

Fluorescence assays

SDS-PAGE

LC/MS

Mass spectrometry

Job description

Sail Biomedicines is seeking a Senior Research Associate to join the Targeted Drug Delivery team. This onsite, lab-based role supports the development of targeted lipid nanoparticle formulations for nucleic acid delivery.

The role requires hands-on experiments, collaboration with cross-functional teams, and meticulous data recording to advance Sail’s delivery platform. 1–3+ years in related fields is preferred.