LNP Discovery Scientist — Formulation & Delivery Innovation

Socket.dev; South San Francisco (CA); On-site; USD 90,000 - 103,000; Full time

Job summary

Addition Therapeutics, based in South San Francisco, seeks a contract SRA/Scientist in LNP discovery to design, produce, and optimize lipid nanoparticle formulations for preclinical studies. The role requires hands-on formulation work, data analysis, and cross-functional collaboration across RNA delivery programs.

The successful candidate will contribute to the delivery platform, work with RNA processing and analytical teams, and travel 15% to CRO sites for in vivo work. On-site in SSF.

Qualifications

• PhD in a relevant field with 1-3 years of industry or research experience.
• BS +5 years or MS +3 years in LNP formulation and RNA delivery.
• Experience with LNP analytical methods and physicochemical attributes.

Responsibilities

• Design, formulate, and characterize LNP formulations for in vitro and in vivo studies.
• Execute LNP production using microfluidic and jet mixing for reproducibility and scale.
• Coordinate with CROs and travel to in vivo study sites for dosing materials.
• Maintain rigorous ELN documentation and present data at cross-functional meetings.

Skills

LNP formulation

LNP production

RiboGreen assays

DLS

zeta-potential

RNA extraction

capillary electrophoresis

endotoxin testing

TNS assay

in vivo study coordination

drug delivery systems

Education

PhD in Chemistry, Biology, Chemical Engineering, Biochemical Engineering, Pharmaceutical Sciences, or related field

BS with 5+ years experience in relevant field

MS with 3+ years experience in relevant field

Tools

Dialysis

Ultrafiltration

Tangential Flow Filtration

Sterile filtration

Job description

Addition Therapeutics, based in South San Francisco, seeks a contract SRA/Scientist in LNP discovery to design, produce, and optimize lipid nanoparticle formulations for preclinical studies. The role requires hands-on formulation work, data analysis, and cross-functional collaboration across RNA delivery programs.

The successful candidate will contribute to the delivery platform, work with RNA processing and analytical teams, and travel 15% to CRO sites for in vivo work. On-site in SSF.