Senior Lab Automation Engineer — High-Throughput DNA Workflows

twistbioscience; South San Francisco (CA); On-site; USD 140,000 - 169,000; Full time

Job summary

Twist Bioscience is seeking a Sr Automation Engineer to be onsite in South San Francisco, CA. You will deploy automated solutions to Twist back-end operations, specializing in Hamilton STAR, and develop, validate, and maintain automated liquid handling methods.

Reporting within the Engineering organization, you will collaborate with Operations, R&D, and Quality to release robust automated workflows in a fast-paced environment, ensuring compliance with ISO 13485 quality standards and integration

Qualifications

• B.S. or M.S. in Engineering, Life Sciences, or related field.
• 7+ years in laboratory automation.
• 5+ years with Hamilton Robotics systems.
• Experience writing software requirements and interfaces with LIMS.
• Strong data analysis and problem-solving skills.

Responsibilities

• Develop, validate, and maintain automated liquid handling methods supporting high-throughput workflows across Twist's synthetic biology and genomics product lines
• Provide hands-on support for liquid handlers, bulk dispensers, analytical instrumentation, sequencers, and integrated automation systems
• Lead validation projects, author technical documentation, and maintain existing production systems.
• Collaborate within cross-functional teams to optimize existing processes, gather requirements for new processes, and integrate hardware with Twist LIMS
• Evaluate instrument manufacturers' native software and automation offerings, communicate integration needs, and build in-house solutions when needed

Skills

Laboratory automation

Robotics operation

Data analysis

Problem solving

LIMS interfaces

NGS automation

Education

B.S./M.S. in Engineering

Life Sciences

Tools

Hamilton Robotics

Python

C#

VBScript

Job description

Twist Bioscience is seeking a Sr Automation Engineer to be onsite in South San Francisco, CA. You will deploy automated solutions to Twist back-end operations, specializing in Hamilton STAR, and develop, validate, and maintain automated liquid handling methods.

Reporting within the Engineering organization, you will collaborate with Operations, R&D, and Quality to release robust automated workflows in a fast-paced environment, ensuring compliance with ISO 13485 quality standards and integration