Senior IT Systems Engineer — Lab IT & Windows Lead

Slipstream Co; South San Francisco (CA); On-site; USD 135,000 - 145,000; Full time

Benefits offered by this job

401k match

Comprehensive health benefits

Life insurance

Job summary

Slipstream Life Sciences seeks a Senior IT Systems Engineer to lead Windows server and directory services administration in our South San Francisco lab environment. You will partner with lab operations, automation and software engineering to keep systems secure, patched, and integrated with the broader IT ecosystem.

This role demands strong technical judgment, excellent communication, and the ability to drive improvements, define testing plans, and deliver complex projects from requirements

Qualifications

• Bachelor's degree and 8+ years of relevant experience in biotech or medtech lab IT environment.
• Deep hands-on experience with Windows Server, Active Directory, Group Policy, and system hardening.
• Experience triaging vulnerability findings and maintaining secure configuration baselines.
• Written technical specifications and architecture documents for complex projects.
• Ability to plan, build and deliver projects with minimal formal authority.

Responsibilities

• Administer Windows server and directory environment (Active Directory, Group Policy, hardening).
• Support storage, networking, and PC management for laboratory computing.
• Onboard, patch, secure, and integrate instruments and complex workcells computers.
• Maintain asset records through lifecycle (licensing, maintenance, replacement).
• Participate in on-call rotation for critical IT issues.
• Define testing and mitigation plans for proposed changes.
• Investigate root causes of incidents and implement preventative changes.
• Contribute to security governance and compliance.

Skills

Strong communication

Leadership

Documentation

Project planning

Problem solving

Education

Bachelor's degree

Tools

Active Directory

Group Policy

Windows Server

PowerShell

Python

Bash

Job description

Slipstream Life Sciences seeks a Senior IT Systems Engineer to lead Windows server and directory services administration in our South San Francisco lab environment. You will partner with lab operations, automation and software engineering to keep systems secure, patched, and integrated with the broader IT ecosystem.

This role demands strong technical judgment, excellent communication, and the ability to drive improvements, define testing plans, and deliver complex projects from requirements