Senior Infrastructure Engineer — On-Prem, High Availability

Baylor Genetics; Houston (TX); On-site; USD 120,000 - 160,000; Full time

Job summary

Baylor Genetics in Houston seeks a Senior Infrastructure Engineer to serve as backup for the on‑premises data center, ensuring uninterrupted operation of critical systems across genomics pipelines and clinical labs.

You will maintain servers, storage, and networks (Windows Server, Linux, VMware/Hyper‑V), manage data center operations, and develop runbooks and disaster‑recovery docs to eliminate single points of failure while supporting patient‑impacting workflows.

Qualifications

• Bachelor’s degree in IT, CS, or equivalent experience.
• 7+ years of hands-on enterprise IT infrastructure engineering in on-premises environments.
• Deep server administration across Windows Server and Linux with VMware/Hyper‑V.
• Strong networking, including routing, switching, VLANs, and firewall management.
• Experience managing data center racks, cabling, power, and cooling.
• Proficiency with SAN/NAS storage and backup systems (Veeam/Commvault).
• Knowledge of Microsoft 365 and Azure AD in hybrid contexts.
• Excellent runbook and SOP documentation; independent problem solving.

Responsibilities

• Act as backup for primary infrastructure lead to ensure zero service interruption.
• Administer and maintain data center servers, storage, and network infrastructure.
• Manage LAN/WAN, switches, routers, firewalls, and VLANs for high availability.
• Create and maintain runbooks, diagrams, and disaster recovery docs.
• Support genomics pipeline infrastructure with required throughput and availability.
• Collaborate with bioinformatics, clinical lab, and IT teams.
• Identify and remediate risks, including aging hardware and config vulnerabilities.
• Respond to incidents, including after-hours escalations.
• Perform other duties as assigned.
• Comply with policies, procedures, and regulatory requirements.

Skills

IT infrastructure engineering

Windows Server

Linux

VMware vSphere

Hyper-V

Networking

Data center operations

SAN/NAS storage

Veeam/Commvault backups

Microsoft 365

Azure AD

Education

Bachelor’s degree in IT/CS or related field

Equivalent experience

Tools

VMware vSphere

Microsoft Hyper-V

Veeam

Commvault

Cisco networking

Palo Alto / Fortinet firewalls

Microsoft 365

Azure AD

Job description

Baylor Genetics in Houston seeks a Senior Infrastructure Engineer to serve as backup for the on‑premises data center, ensuring uninterrupted operation of critical systems across genomics pipelines and clinical labs.

You will maintain servers, storage, and networks (Windows Server, Linux, VMware/Hyper‑V), manage data center operations, and develop runbooks and disaster‑recovery docs to eliminate single points of failure while supporting patient‑impacting workflows.