Senior In Vitro Biologist - Cancer Translational Research

Cogent Scientific; Indianapolis (IN); On-site; USD 90,000 - 140,000; Full time

Benefits offered by this job

Medical/dental/vision insurance

401(k)

Parental leave

PTO and paid holidays

Relocation benefits

Job summary

Cogent Scientific in Indianapolis, IN is seeking an Expert In Vitro Biologist to advance oncology programs through in vitro and in vivo assays.

You will lead design and execution of complex cell-based studies and flow cytometry panels, collaborating across teams to translate findings into actionable strategies.

This onsite role offers a fast-paced environment with opportunities to contribute to impactful cancer biology research.

Qualifications

• Ph.D. in biology, cancer biology, immunology, biochemistry, or a related discipline with 1-3 years of relevant laboratory experience in drug discovery/cancer biology.
• BS (8-10 years experience) or MS (5-8 years experience) will also be considered.
• Hands-on experience with multi-color flow cytometry, including panel design, sample preparation, acquisition, and data analysis.
• Demonstrated experience designing and executing in vitro tumor cell–based assays.
• Hands-on experience with in vivo xenograft tumor models, including study design, and endpoint sample analysis.
• Excellent attention to detail.
• Ability to work well both independently and within a team.
• Very strong problem-solving skills, a high level of learning agility, and the ability to work across functions.

Responsibilities

• Contribute to mechanism-of-action, target engagement, and translational study components across the AML, colorectal cancer, and breast cancer programs.
• Design, execute, and interpret in vitro tumor cell assays (e.g., viability/proliferation, apoptosis, cell cycle, target engagement, and pathway-modulation assays) to characterize compound activity and inform program decisions.
• Design, conduct, and analyze in vivo xenograft tumor model studies — including dosing, tumor measurement, and PK/PD endpoint sample collection — to establish efficacy and mechanistic relationships.
• Design and run multi-color flow cytometry panels for immunophenotyping, target expression, and pathway-modulation analysis of cell lines and tumor-, blood-, or tissue-derived samples.

Skills

Multi-color flow cytometry

In vitro tumor cell assays

In vivo xenograft tumor models

Independent work and teamwork

Problem-solving & leadership

Education

Ph.D. in biology, cancer biology, immunology, biochemistry, or related discipline

BS/MS considered with extensive lab experience

Tools

Flow cytometer operation

In vivo study design tools

Job description

Cogent Scientific in Indianapolis, IN is seeking an Expert In Vitro Biologist to advance oncology programs through in vitro and in vivo assays.

You will lead design and execution of complex cell-based studies and flow cytometry panels, collaborating across teams to translate findings into actionable strategies.

This onsite role offers a fast-paced environment with opportunities to contribute to impactful cancer biology research.