Expert In Vitro Biologist

Cogent Scientific; New York (NY); On-site; USD 110,000 - 170,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401(k)

Parental leave

Paid holidays

Job summary

Cogent Scientific is seeking an Expert In Vitro Biologist to establish and optimize patient-derived organoid cultures and robust co-culture systems. The role involves developing 3D organotypic models and assays for early drug discovery, with emphasis on cancer biology and tumor microenvironment interactions.

You will work in a fast-paced, cross-functional environment, applying cutting-edge imaging and molecular techniques to generate actionable insights while collaborating with teams across

Qualifications

• PhD in cell biology or MS with 4+ years of research experience.
• Experience with patient-derived or tumor-related models is a plus.
• Strong molecular biology and imaging technique background required.
• Excellent communication and collaboration skills.
• Ability to work independently and in cross-functional teams.

Responsibilities

• Establish, expand, and maintain organoid cultures from patient-derived material.
• Develop and optimize complex co-culture models with multiple cell types.
• Create and optimize in vitro assays using 3D models for discovery oncology.
• Design semi- or high-throughput assays using advanced microscopy.
• Perform 3D cell culture assays and analyze various readouts.

Skills

Communication skills

Team player

Leadership potential

Learning agility

Education

PhD in cell biology

MS with 4+ years experience

Tools

IF

IHC

Western blot

Flow cytometry

Confocal microscopy

Light sheet imaging

Job description

Company Overview

Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to support the life sciences industry by cultivating and empowering exceptional scientists to deliver specialized laboratory services that advance research, foster collaboration, and accelerate innovation through quality and a shared commitment to excellence. We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation.

Cogent Scientific offers competitive pay, attractive benefits (such as medical/dental/vision insurance; 401(k); parental leave; PTO and paid holidays; etc.) and an exciting work environment. This position may include relocation benefits as well. We aim to recruit the best people who stand out among their peers and embody our Core Values:

• Client Focused: We only succeed when our clients succeed.
• Outstanding: We deliver meticulous results through outstanding performance.
• Good: We act ethically and morally.
• Employee-Centric: We honor and support our employees.
• Nimble: We are prepared to adapt in an ever-changing industry.
• Team-Oriented: We collaborate with each other and with our clients.

We currently have a role available for an Expert In Vitro Biologist.

Job duties

• Establish, expand, and maintain patient-derived and tissue-specific organoid cultures. Independently optimize protocols for improved fidelity, maturation, and biological relevance.
• Independently develop, troubleshoot, and improve complex co-culture model systems incorporating primary human tumor cells, fibroblasts, immune cells, and microenvironment components to deliver robust scientific answers.
• Establish and optimize novel in vitro assays using 3D organotypic models, complex co-cultures, organoids, transwell systems, air-liquid interface, and/or organ-on-a-chip platforms representing both healthy and disease states to support discovery oncology programs.
• Design and execute semi- or high-throughput endpoint and kinetic assays for safety and efficacy screening of molecules during early discovery using advanced microscopy.
• Perform 3D cell culture assays, including viability, proliferation, differentiation, and drug response studies, using cellular and molecular biology techniques such as CellTiter-Glo, Western blotting, ELISA, flow cytometry, and immunofluorescence staining.

Job requirements

• PhD in cell biology, bioengineering, cancer biology, or a related discipline; or MS in a related field with 4+ years of relevant research experience.
• Working knowledge of at least one of the focus areas: renal, pancreatic, lung, or colon biology.
• Experience with molecular biology techniques such as IF, IHC, western blotting, and flow cytometry.
• Experience with advanced microscopy techniques (confocal, light sheet, high-content imaging) for assessing the phenotype of complex models and kinetic assays.
• Excellent communication skills - verbal and written.

• Works well both as a team and as an individual.
• Demonstration of excellent team player skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions. The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.

This is a day shift position (approx. 8a-5p local time).

Cogent Scientific provides equal employment opportunities to all applicants and does not discriminate based on any legally protected characteristic.

Additionally, if you require a reasonable accommodation during the application or interview process, please let us know.

This job posting will remain open until 9/14/2026 or until a qualified candidate has been selected, whichever comes first.