Expert In Vitro Biologist

Cogent Scientific

Indianapolis (IN)

On-site

USD 90,000 - 140,000

Full time

10 days ago

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Benefits offered by this job

Medical/dental/vision insurance

401(k)

Parental leave

PTO and paid holidays

Relocation benefits

Job summary

Cogent Scientific in Indianapolis, IN is seeking an Expert In Vitro Biologist to advance oncology programs through in vitro and in vivo assays.

You will lead design and execution of complex cell-based studies and flow cytometry panels, collaborating across teams to translate findings into actionable strategies.

This onsite role offers a fast-paced environment with opportunities to contribute to impactful cancer biology research.

Qualifications

Ph.D. in biology, cancer biology, immunology, biochemistry, or a related discipline with 1-3 years of relevant laboratory experience in drug discovery/cancer biology.
BS (8-10 years experience) or MS (5-8 years experience) will also be considered.
Hands-on experience with multi-color flow cytometry, including panel design, sample preparation, acquisition, and data analysis.
Demonstrated experience designing and executing in vitro tumor cell–based assays.
Hands-on experience with in vivo xenograft tumor models, including study design, and endpoint sample analysis.
Excellent attention to detail.
Ability to work well both independently and within a team.
Very strong problem-solving skills, a high level of learning agility, and the ability to work across functions.

Responsibilities

Contribute to mechanism-of-action, target engagement, and translational study components across the AML, colorectal cancer, and breast cancer programs.
Design, execute, and interpret in vitro tumor cell assays (e.g., viability/proliferation, apoptosis, cell cycle, target engagement, and pathway-modulation assays) to characterize compound activity and inform program decisions.
Design, conduct, and analyze in vivo xenograft tumor model studies — including dosing, tumor measurement, and PK/PD endpoint sample collection — to establish efficacy and mechanistic relationships.
Design and run multi-color flow cytometry panels for immunophenotyping, target expression, and pathway-modulation analysis of cell lines and tumor-, blood-, or tissue-derived samples.

Skills

Multi-color flow cytometry

In vitro tumor cell assays

In vivo xenograft tumor models

Independent work and teamwork

Problem-solving & leadership

Education

Ph.D. in biology, cancer biology, immunology, biochemistry, or related discipline

BS/MS considered with extensive lab experience

Tools

Flow cytometer operation

In vivo study design tools

Job description

Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to support the life sciences industry by cultivating and empowering exceptional scientists to deliver specialized laboratory services that advance research, foster collaboration, and accelerate innovation through quality and a shared commitment to excellence. We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation.

Cogent Scientific offers competitive pay, attractive benefits (such as medical/dental/vision insurance; 401(k); parental leave; PTO and paid holidays; etc.) and an exciting work environment. This position may include relocation benefits as well. We aim to recruit the best people who stand out among their peers and embody our Core Values:

Client Focused: We only succeed when our clients succeed.
Outstanding: We deliver meticulous results through outstanding performance.
Good: We act ethically and morally.
Employee-Centric: We honor and support our employees.
Nimble: We are prepared to adapt in an ever-changing industry.
Team-Oriented: We collaborate with each other and with our clients.

We currently have a role available for an Expert In Vitro Biologist.

Job duties include, but are not limited to, the following:

Contribute to mechanism-of-action, target engagement, and translational study components across the AML, colorectal cancer, and breast cancer programs.
Design, execute, and interpret in vitro tumor cell assays (e.g., viability/proliferation, apoptosis, cell cycle, target engagement, and pathway-modulation assays) to characterize compound activity and inform program decisions.
Design, conduct, and analyze in vivo xenograft tumor model studies — including dosing, tumor measurement, and PK/PD endpoint sample collection — to establish efficacy and mechanistic relationships.
Design and run multi-color flow cytometry panels for immunophenotyping, target expression, and pathway-modulation analysis of cell lines and tumor-, blood-, or tissue-derived samples.

Job requirements include, but are not limited to, the following:

Ph.D. in biology, cancer biology, immunology, biochemistry, or a related discipline with 1-3 years of relevant laboratory experience in drug discovery/cancer biology.
- BS (8-10 years experience) or MS (5-8 years experience) will also be considered.
Hands-on experience with multi-color flow cytometry, including panel design, sample preparation, acquisition, and data analysis.
Demonstrated experience designing and executing in vitro tumor cell–based assays.
Hands-on experience with in vivo xenograft tumor models, including study design, and endpoint sample analysis.
Excellent attention to detail.
Ability to work well both independently and within a team.
Very strong problem-solving skills, a high level of learning agility, and the ability to work across functions.
The ideal candidate should be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.