Senior HPC Infrastructure Engineer – Remote

Guardant Health, Inc.

United States

Hybrid

USD 156,000 - 214,000

Full time

14 days+

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Job summary

Guardant Health, Inc. is seeking a Senior HPC Infrastructure Engineer to manage multiple HPC clusters, storage, and networking, advancing scalable infrastructure to support research and production workflows.

You will mentor junior engineers, collaborate with cross-functional teams, and help implement next-generation HPC solutions across on-prem and cloud environments while upholding security and reliability standards.

Qualifications

Bachelor’s degree in Computer Science or a related field; required 8–12 years of relevant experience.
Master’s degree with 6–8 years of relevant experience; PhD with 3–5 years acceptable.
Strong experience in systems and/or infrastructure engineering, including Linux/Unix administration and TCP/IP networking.

Responsibilities

Manage multiple HPC clusters and cluster file systems.
Integrate cloud bursting as part of the HPC abstraction work.
Research, develop, and implement the next generation HPC solutions.
Troubleshoot the production system stack down to source code level.
Maintain, monitor, and support the infrastructure environment and/or facilities.
Mentor junior engineers on HPC best practices.
Work with offsite consultants and vendors to maintain the infrastructure.
Participate in a 24/7 on-call rotation.
Set up and ownership supporting HPC metric monitoring.