Senior Genomics Data Scientist – DRAGEN & ICA

Illumina; United States; Hybrid; USD 59,000 - 88,000; Full time

Job summary

Illumina seeks a Senior Bioinformatics Scientist to join the team driving the industry‑leading DRAGEN platform and its integration with Illumina Connected Analytics (ICA). You will develop next‑generation bioinformatics solutions turning complex genomic data into meaningful insights, tackling challenges in oncology, rare diseases, and population genomics.

You will design scalable algorithms, collaborate with cross‑functional teams, and contribute to widely adopted secondary analysis workflows

Qualifications

• Master’s or PhD in Bioinformatics, Computer Science, Statistics, Engineering, or a related discipline.
• Strong experience developing bioinformatics methods and algorithms for next‑generation sequencing data.
• Expertise in secondary analysis workflows including mapping, alignment, variant calling, and genomic interpretation.
• Proficiency in C/C++, or equivalent high‑performance programming languages.
• Experience working with large‑scale genomic datasets and production software environments.
• Knowledge of applications such as cancer genomics, rare disease analysis, population genetics, transcriptomics, or multi‑omics research.

Responsibilities

• Design, develop, and implement innovative computational and statistical methods for genomic data analysis.
• Build high‑performance production software that delivers speed, scalability, and accuracy.
• Analyze and interpret complex sequencing datasets to support product and workflow development.
• Partner with software, FPGA, quality, clinical genomics, and product teams to deliver integrated solutions.
• Advance the DRAGEN platform across germline, somatic, DNA, RNA, structural variant, CNV, and targeted sequencing applications.
• Engage with customers, researchers, and scientific collaborators to understand emerging needs.
• Present scientific findings and technical approaches to both specialist and non‑specialist audiences.
• Contribute to publications, presentations, technical documentation, and thought leadership initiatives.
• Evaluate and apply emerging technologies to continuously improve performance and customer outcomes.
• Champion collaboration, accountability, and innovation while helping teams succeed together.

Skills

C/C++

Genomics

Bioinformatics

Algorithms

Statistics

Education

Master’s or PhD in Bioinformatics, Computer Science, Statistics, Engineering, or related

Tools

DRAGEN

Illumina ICA

Job description

Illumina seeks a Senior Bioinformatics Scientist to join the team driving the industry‑leading DRAGEN platform and its integration with Illumina Connected Analytics (ICA). You will develop next‑generation bioinformatics solutions turning complex genomic data into meaningful insights, tackling challenges in oncology, rare diseases, and population genomics.

You will design scalable algorithms, collaborate with cross‑functional teams, and contribute to widely adopted secondary analysis workflows