Director Clinical Bioinformatics

Illumina; San Diego (CA); On-site; USD 205,000 - 308,000; Full time

Job summary

Illumina seeks a Director of Clinical Bioinformatics based in the U.S. to lead informatics for end-to-end assay and application solutions. The role requires driving innovative algorithms on the DRAGEN platform and managing multi-disciplinary teams to advance precision medicine.

The ideal candidate will have extensive experience in regulated LDTs/IVD environments, and a proven ability to deliver major projects from concept to market. Travel to San Diego is expected.

Qualifications

• Bachelor’s degree and 18+ years of related experience, with 10+ years of management experience.
• Proven track record leading major multi-disciplinary product development projects from concept to commercial release.
• Extensive experience developing bioinformatics algorithms for NGS and microarray across oncology, genetics, and reproductive health.
• Broad experience building regulated LDTs, distributed IVD products, or regulated instrument systems.

Responsibilities

• Lead bioinformatics for design, delivery, and validation of end-to-end assay and application solutions.
• Innovate to deliver high-value solutions for precision medicine and multi-omics applications.
• Design and implement novel bioinformatics algorithms on the DRAGEN platform.
• Build and manage relationships with external customers, partners, and key opinion leaders; represent Illumina externally.
• Develop programs to monitor and respond to competitive technologies.

Skills

Bioinformatics

Leadership

Communication

Strategic planning

Education

Bachelor's degree

Tools

DRAGEN platform

Job description

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Illumina is seeking a Director of Clinical Bioinformatics to lead delivery of informatic solutions that power Illumina’s end-to-end solutions and assay informatics. We are looking for an experienced bioinformatics leader that is passionate about powering new applications with innovative new informatics approaches using Illumina sequencing and multi-omic technologies. This is a unique opportunity to be a core contributor to Illumina’s mission to unlock the power of the genome by creating our next application solutions and industry leading bioinformatic algorithms.

Location

The ideal candidate is based in San Diego, CA or within California with the ability to travel to San Diego on a regular basis.

Responsibilities

• Lead bioinformatics for design, delivery, and validation of end-to-end assay and application solutions.
• Innovate vigorously to deliver high value solutions to drive next wave of precision medicine and multi-omics applications
• Responsible for design and implementation of novel bioinformatics algorithms on the DRAGEN platform
• Build and manage relationships with external customers, partners, and key opinion leaders and represent Illumina externally
• Develop program to proactively monitor, and tactically and strategically respond to competitive technologies

Requirements

• Typically requires a Bachelor’s degree and a minimum of 18 years of related experience, with 10+ years of Management experience.
• Proven track record of successfully leading major multi-disciplinary product development projects from concept to commercial release
• Extensive experience developing Bioinformatics algorithms for multiple technologies (NGS and microarray) and domain areas (oncology, genetics, and reproductive health)
• Broad experience building regulated lab developed tests, distributed IVD products, or regulated instrument systems
• Must effectively balance innovation roadmap with execution-oriented product development projects
• Exceptional communication skills
• Able to deliver result in uncertain and fast-paced environment
• Results oriented leader with 5+ years leading globally distributed teams; must have experience managing managers
• #LI-REMOTE

Salary & Benefits

The estimated base salary range for the Director Clinical Bioinformatics role based in the United States of America is: $205,100 - $307,700. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

Company Culture & Inclusion

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility.

We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.

Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws.

Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [e-mail].

To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf.

This role is not eligible for visa sponsorship.

The potential of genomics to change the world is unparalleled. At Illumina, we are leading the way. Our technology empowers researchers and clinicians globally to improve cancer treatments, change the course of diseases, protect the environment, and fight food insecurity. We are made up of dedicated professionals, all-in on creating a better world – and we need every skill set on our path to making genomics useful for all.