Senior Full-Stack Software Engineer (Machine Learning)

Clairyon; San Diego (CA); On-site; USD 120,000 - 160,000; Full time

Job summary

Clairyon is hiring a Senior Full-Stack Software Engineer (Machine Learning) to design, develop, and maintain web applications powering the clinical AI platform. The role focuses on front-end interfaces, back-end services, and production-grade machine-learning integrations, with API development for real-time clinical and sensor data.

You will work with data scientists, clinicians, and product teams to translate research models and workflows into scalable software, while participating in

Qualifications

• Proficient in Python and TypeScript with end-to-end feature ownership.
• Experience building secure, scalable APIs and services.
• Experience deploying ML models in production and monitoring performance.
• Experience with AI agents and RAG architectures.
• Cloud, containerization, CI/CD using AWS, Docker, Kubernetes.
• Healthcare data experience and HIPAA knowledge is beneficial.

Responsibilities

• Design, develop, and maintain end-to-end web applications powering Clairyon's clinical AI platform.
• Implement production-grade ML integrations and APIs ingesting real-time data.
• Collaborate with data scientists, clinicians, and product teams to translate research into software.
• Contribute to code reviews, testing, documentation, and architectural decisions across the engineering organization.

Skills

Python

TypeScript

Full-Stack Development

Machine Learning integrations

APIs

LangChain

LangFlow

DSPy

Education

Bachelor's or Master's in Computer Science, Engineering, or related field

5+ years of relevant experience

Tools

AWS

Docker

Kubernetes

CI/CD

SQL/NoSQL databases

Job description

Company Description

Clairyon Inc. is a clinical artificial intelligence company focused on transforming acute care and patient monitoring through predictive analytics and agentic AI. Built on research from leading academic institutions, Clairyon offers the CLAIRE Continuum of Care Platform, a comprehensive ecosystem of advanced clinical decision support tools. This includes the COMPOSER predictive model, which has demonstrated significant reductions in sepsis mortality, and robust post-discharge and quality monitoring solutions validated in top medical journals. By combining longitudinal electronic health records with real-time biometric sensor data, the platform enables proactive detection of high-risk conditions, automated care quality monitoring, and improved clinical documentation. Team members collaborate in a mission-driven environment aimed at improving outcomes from the emergency department to the home.

Role Description

This is a full-time, on-site role based in San Diego, CA for a Senior Full-Stack Software Engineer (Machine Learning). The person in this role will design, develop, and maintain end-to-end web applications that power Clairyon's clinical AI platform, including both front-end user interfaces and back-end services. Daily responsibilities include implementing production-grade machine learning integrations, building APIs to ingest and process real-time clinical and sensor data, and optimizing data pipelines and model serving infrastructure for performance, reliability, and security. The engineer will collaborate closely with data scientists, clinicians, and product teams to translate research models and clinical workflows into scalable, user-centric software solutions. Additional tasks include code reviews, unit and integration testing, documentation, and contributing to architectural decisions and best practices across the engineering organization.

Qualifications

• Demonstrated proficiency in Full-Stack and Software Development, with strong hands-on experience in Python and TypeScript, including experience owning features from design to deployment.
• Strong Back-End Web Development skills, with experience building secure, scalable APIs and services.
• Experience integrating machine learning models into production systems, including model deployment, performance monitoring, and iterative improvement.
• Strong, hands-on experience building AI agents and RAG architectures using modern orchestration tools (LangChain, LangFlow, DSPy).
• Solid understanding of cloud platforms (e.g., AWS), containerization (Docker, Kubernetes), and CI/CD pipelines.
• Proficiency with relational and non-relational databases, data modeling, and efficient query design for high-volume clinical or sensor data.
• Experience with clinical and device data, including healthcare interoperability standards such as HL7 FHIR.
• Experience in healthcare, healthtech, or regulated environments (HIPAA, security and compliance standards) is highly beneficial.
• Commitment to writing clean, testable code and maintaining high engineering standards in a mission-driven setting.
• Bachelor's or Master's degree in Computer Science, Engineering, or a related field, or equivalent practical experience (5+).
• Strong collaboration and communication skills, with the ability to work effectively in cross-functional teams and with clinical stakeholders.