Senior Drug Discovery Researcher - Cellular Rejuvenation

CHEManager International; San Francisco (CA); On-site; USD 109,000 - 140,000; Full time

Job summary

Altos Labs seeks a Senior Research Associate to support drug discovery and development by executing a wide range of biological and bioanalytical assays. The role centers on aging biology and cellular rejuvenation, contributing to a portfolio of therapeutic projects.

You will work collaboratively within the Drug Discovery team, maintaining high data standards, presenting findings, and contributing to the bench-heavy efforts essential to advancing our lead candidates.

Qualifications

• BS or MS in Molecular Biology, Cell Biology, Biochemistry, Bioengineering, or related discipline with 5+ years in drug discovery.
• Strong expertise in AAV gene therapy cell-based assays and genome titration.
• Experience with analytical and bioassays with solid data analysis and statistics.
• Experience with MSD, HTRF, AlphaLISA, Luminex, etc.
• Automation platforms (Bravo, Echo, I.DOT, Digital dispenser) on bench.
• Proficient in documenting experimental design, analysis and data interpretation in ELN.

Responsibilities

• Drive drug discovery and development projects with scientific manager.
• Culture and maintain mammalian cells and manage reagents.
• Design, optimize, automate, execute and troubleshoot a range of cellular and biochemical assays.
• Standardize assay protocols and draft SOPs.
• Document methods, data and results in ELN with reproducibility in mind.
• Present data at project team meetings to support decisions.
• Approx. 80% time on benchtop science.

Skills

AAV gene therapy assays

qPCR / ddPCR

RT-qPCR / ddPCR

Western Blot / ELISA

Data analysis & statistics

Education

BS or MS in Molecular Biology/Cell Biology/Biochemistry/ Bioengineering

Tools

ELN

Automation platforms (Bravo, Echo, I.DOT)

Job description

Altos Labs seeks a Senior Research Associate to support drug discovery and development by executing a wide range of biological and bioanalytical assays. The role centers on aging biology and cellular rejuvenation, contributing to a portfolio of therapeutic projects.

You will work collaboratively within the Drug Discovery team, maintaining high data standards, presenting findings, and contributing to the bench-heavy efforts essential to advancing our lead candidates.