Senior Medicinal Chemist — Drug Discovery Leader

CHEManager International; San Francisco (CA); On-site; USD 175,000 - 316,000; Full time

Job summary

Altos Labs in California seeks a talented Medicinal Chemist to join the small-molecule drug discovery team. You will advance science from hit identification to lead optimization in a collaborative, fast-paced environment. The ideal candidate holds a Ph.D.

in Organic Chemistry with 6+ years post-PhD experience, proven expertise in synthetic/medicinal chemistry, and a track record in drug discovery. This role offers leadership potential and close work with CROs, across locations in Redwood City

Qualifications

• Ph.D. in Organic Chemistry with 6+ years post-PhD experience.
• Proven expertise in modern synthetic medicinal chemistry and related methods.
• Experience in drug discovery from hit identification to lead optimization.

Responsibilities

• Drive drug discovery programs by designing drug-like molecules and optimizing compounds toward development candidates.
• Collaborate cross-functionally with DMPK, Structural Biology, Biochemical/Cellular Pharmacology, ML, and CROs.
• Design and synthesize novel compounds using structure-, computation-, and property-based design tools; perform SAR analyses.
• Analyze data to inform design decisions and communicate results to internal/external stakeholders.

Skills

Synthetic/MedChem

Lead optimization

Structure-based drug design

Collaboration

Communication skills

Education

Ph.D. in Organic Chemistry

Job description

Altos Labs in California seeks a talented Medicinal Chemist to join the small-molecule drug discovery team. You will advance science from hit identification to lead optimization in a collaborative, fast-paced environment. The ideal candidate holds a Ph.D.

in Organic Chemistry with 6+ years post-PhD experience, proven expertise in synthetic/medicinal chemistry, and a track record in drug discovery. This role offers leadership potential and close work with CROs, across locations in Redwood City