Senior DMPK Scientist — Flexible Schedule & Equity

Schrödinger; Cambridge (MA); On-site; USD 170,000 - 290,000; Full time

Benefits offered by this job

Salary + equity

Healthcare (medical, dental, vision)

401k

Commuter benefits

Flexible schedule

Parental leave

Paid vacation

Job summary

Schrödinger seeks a DMPK Scientist to develop and drive DMPK and PK/PD strategy for drug discovery projects, representing the DMPK group on cross-functional teams and collaborating with CROs to generate data for knowledge integration.

The ideal candidate will have a PhD or Master’s with extensive DMPK experience, strong communication and leadership skills, and a track record of informing regulatory submissions. Schrödinger offers a competitive salary, equity, and comprehensive benefits.

Qualifications

• PhD or Master’s with extensive DMPK experience as stated.
• Experience representing DMPK on project teams and collaboration with CROs.

Responsibilities

• Develop and drive DMPK and PK/PD strategy for drug discovery projects.
• Represent the DMPK group on internal and intercompany project teams to translate modeling into druggable entities.
• Collaborate with internal/external teams and CROs to generate data for knowledge integration.
• Analyze and integrate in silico ADME predictive solutions, physicochemical data, and DMPK data to influence multiparameter optimization.
• Prepare reports for regulatory submissions and support interactions with regulatory agencies.
• Collaborate on establishing predictive computational ADME/DMPK models.

Skills

DMPK expertise

ADME knowledge

Data analysis

Scientific presentation

Education

PhD in life sciences or related with 5+ years DMPK experience

Master’s degree with 10+ years DMPK experience

Tools

Phoenix/WinNonlin

SimCYP

Monolix

MATLAB SimBiology

Job description

Schrödinger seeks a DMPK Scientist to develop and drive DMPK and PK/PD strategy for drug discovery projects, representing the DMPK group on cross-functional teams and collaborating with CROs to generate data for knowledge integration.

The ideal candidate will have a PhD or Master’s with extensive DMPK experience, strong communication and leadership skills, and a track record of informing regulatory submissions. Schrödinger offers a competitive salary, equity, and comprehensive benefits.