Senior Director, Translational Oncology Biomarkers

Verastem Oncology; Needham (MA); On-site; USD 210,000 - 265,000; Full time

Benefits offered by this job

Annual bonus

Equity compensation

Competitive benefits package

Job summary

Verastem Oncology is seeking a highly motivated Senior Director of Translational Research with oncology and biomarker experience to lead the development and execution of biomarker and pharmacodynamic strategies across clinical programs.

The Translational Research Scientist will oversee biospecimen management, vendor oversight, biomarker data analysis, and reporting, coordinating across cross-functional teams to advance translational strategies and inform patient selection and drug combinations.

Qualifications

• Ph.D. in cancer biology or related field with 12+ years of industry oncology experience.
• Deep knowledge of oncogenic signaling, tumor dependencies, and therapy resistance.
• Experience with biomarker research and pharmacodynamic analyses in oncology.
• Familiarity with clinical biospecimen workflows and external biomarker vendors.
• Excellent written and verbal communication; strong cross-functional collaboration.

Responsibilities

• Lead development and execution of biomarker and pharmacodynamic strategies for Verastem clinical studies.
• Collaborate with preclinical teams to design translational studies informing indication, pharmacodynamics, and combos.
• Analyze, interpret, and present biomarker data to support clinical decisions.
• Integrate biomarker findings with clinical and preclinical data to generate translational hypotheses.
• Oversee external vendors for biospecimen storage, assays, and bioinformatics analyses.
• Review literature and data, and present at conferences to stay current.
• Contribute to regulatory submissions, study reports, manuscripts, and abstracts.
• Coordinate findings across Translational Medicine, Clinical Development, Bioinformatics, Biostatistics, and Legal.

Skills

Translational research

Biomarker analysis

Oncology

Cross-functional collaboration

Regulatory submissions

Scientific communication

Project management

Education

Ph.D. in cancer biology or related discipline

Tools

Bioinformatics analyses

Biomarker assays

Clinical biospecimen workflows

Job description

Verastem Oncology is seeking a highly motivated Senior Director of Translational Research with oncology and biomarker experience to lead the development and execution of biomarker and pharmacodynamic strategies across clinical programs.

The Translational Research Scientist will oversee biospecimen management, vendor oversight, biomarker data analysis, and reporting, coordinating across cross-functional teams to advance translational strategies and inform patient selection and drug combinations.