Senior Director, Translational Onco-Bioinformatics

Moderna Therapeutics; Cambridge (MA); On-site; USD 211,000 - 379,000; Full time

Benefits offered by this job

Competitive healthcare

Well-being resources

Generous time off

Equity/bonus potential

Job summary

Moderna Therapeutics seeks a Senior Director to lead Translational Bioinformatics for Cancer Vaccines and Bioinformatics Research. Define computational translational strategy across the oncology portfolio, guide a skilled team, and translate complex patient, molecular, and clinical data into actionable insights for development decisions.

The role emphasizes leadership in AI/ML, multi-omics integration, and cross‑functional partnerships to shape clinical strategies and future medicines.

Qualifications

• PhD in bioinformatics, computational biology, immunology, cancer biology, biostatistics, CS, or related field.
• 11+ years of biotech/pharma or related translational experience.
• Proven leadership of computational or translational teams.
• Strong cross-functional collaboration and communication skills.

Responsibilities

• Define and execute translational bioinformatics vision, strategy, and priorities across the oncology portfolio.
• Lead integrated analyses of tumor, immune, multi-omic, and clinical data to understand pharmacodynamics and determinants of response.
• Build partnerships across Clinical Development, Translational Medicine, Biomarkers, Biostatistics, and other functions to align priorities.
• Represent Translational Bioinformatics in scientific forums and governance to support R&D milestones.
• Advance AI/ML and scalable analytics with reusable workflows, ensuring validation and reproducibility.
• Develop and mentor a high-performing team and foster collaboration, autonomy, and accountability.

Skills

Tumor immunology

Cancer genomics

Multi-omics

AI/ML

Python/R

Leadership

Strategic thinking

Education

PhD in Bioinformatics/Computational Biology/Immunology/Cancer Biology/Biostatistics/Computer Science or related

Job description

Moderna Therapeutics seeks a Senior Director to lead Translational Bioinformatics for Cancer Vaccines and Bioinformatics Research. Define computational translational strategy across the oncology portfolio, guide a skilled team, and translate complex patient, molecular, and clinical data into actionable insights for development decisions.

The role emphasizes leadership in AI/ML, multi-omics integration, and cross‑functional partnerships to shape clinical strategies and future medicines.