Senior Director, Quantitative Pharmacology

Penfield Search Partners Ltd.; Princeton (NJ); On-site; USD 180,000 - 240,000; Full time

Job summary

Penfield Search Partners Ltd. is seeking a Senior Director/Director to head the Quantitative Pharmacology group within Translational Medicine at our client’s Princeton, NJ site.

The role reports to the VP of Preclinical Development and Translational Medicine, overseeing pharmacometrics for clinical development candidates and collaborating across discovery, toxicology, regulatory, and late-stage research. The ideal candidate brings 5+ years postdoctoral experience in quantitative

Qualifications

• 5+ years of postdoctoral experience in quantitative pharmacology/pharmacometrics in the biotech and/or pharmaceutical industry.
• Prior experience in the development and application of quantitative methods in drug development.
• Strong background in population PK modeling, exposure-response modeling and analysis, and developing statistical and mechanistic models for drug development.
• Proven track record in clinical research and background in biomedical research.
• Demonstrated record of scientific scholarship and achievement, willingness to work collaboratively across different therapeutic areas.
• Strong interpersonal, writing and presentation skills, as well as the ability to function in a team environment are essential

Responsibilities

• Key member of a product development team, contributing to the advancement of novel chemical entities with a quantitative perspective to support continued investment
• Provide insight and leadership on pharmacokinetic aspects of clinical trials and programs and its application in development strategy
• Drive the implementation of pharmacometric principles and practices
• Development and execution of model-based analyses including translational PK/PD approaches, population pharmacokinetic models, exposure–response models, clinical trial design simulations, and quantitative systems pharmacology (QSP) modeling
• Provide pharmacometric support for programs through the worldwide marketing application filing including supportive registration documents and presentations
• Provide clear, timely communication and interpretation of study results to functional area experts and governance/senior management
• Contribute to assessment of internal and external opportunities
• Interface broadly with key functions including discovery sciences, preclinical development groups, toxicology, clinical operations, drug metabolism, regulatory affairs, and late-stage clinical research
• Mentoring and/or supervision of junior staff to perform above duties and support career development

Skills

Quantitative pharmacology

Pharmacometrics

PK/PD modeling

Population PK

Clinical pharmacology

Data analysis

Education

PhD in quantitative science

Job description

Penfield Search Partners Ltd. is seeking a Senior Director/Director to head the Quantitative Pharmacology group within Translational Medicine at our client’s Princeton, NJ site.

The role reports to the VP of Preclinical Development and Translational Medicine, overseeing pharmacometrics for clinical development candidates and collaborating across discovery, toxicology, regulatory, and late-stage research. The ideal candidate brings 5+ years postdoctoral experience in quantitative