Senior Director, Global HEOR, Hemoglobinopathies

Scorpion Therapeutics; Boston (MA); Hybrid; USD 250,000 - 380,000; Full time

Job summary

Vertex Pharmaceuticals is seeking a Senior Director of Global Health Economics & Outcomes Research to guide HEOR strategy for the Hemoglobinopathies portfolio through development, launch, and post-market phases. You will lead evidence generation, modeling, and HTA activities while coordinating with commercial, medical, and clinical teams.

The role requires a PhD/MD/MPH/PharmD and 12+ years in HEOR, with at least 5+ years in supervision.

Qualifications

• Advanced degree required in a relevant field plus 12+ years in HEOR or related work.
• Expertise in patient-reported outcomes, observational research, health economic modeling, and market access.
• Strong communication, technical, and regulatory knowledge is essential.

Responsibilities

• Develop and execute HEOR strategies across development, launch, and post-market phases.
• Lead HEOR for cross-functional and regional teams.
• Collaborate with commercial, medical, and clinical functions to inform decisions.
• Manage HEOR staff and contribute to evidence dissemination.

Skills

HEOR leadership

Cross-functional leadership

Health economics modeling

Patient-reported outcomes

Regulatory knowledge

Education

PhD/MD/MPH/PharmD

Tools

Budget impact modeling

Job description

Role

Senior Director of Global Health Economics & Outcomes Research (HEOR) leading strategies for Vertex's Hemoglobinopathies (Heme) portfolio through development, launch, and post-market phases.

Responsibilities

• develop and execute HEOR strategies, oversee evidence generation, outcomes research, modeling, and health technology assessments;
• serve as the HEOR lead for cross-functional and regional teams;
• collaborate with commercial, medical, and clinical teams;
• manage HEOR staff.

Requirements

• advanced degree (PhD, MD, MPH, PharmD), 12+ years in HEOR or related field, 5+ years of supervisory experience;
• expertise in patient-reported outcomes, observational research, health economic modeling, and market access;
• strong communication, technical, and regulatory knowledge.

High-Value

• focus on Hemoglobinopathies, biologics or gene therapies, lifecycle management including launch and post-launch, health technology appraisals, payer interactions, and evidence dissemination

WorkSetup

• hybrid or on-site Boston, with flexible work options