Senior Director, Clinical Scientist – FIH Trials (Remote)

Damora Therapeutics; Waltham (MA); Remote; USD 150,000 - 210,000; Full time

Job summary

Damora Therapeutics in Waltham, MA and San Francisco, CA is seeking a Director/Senior Director, Clinical Scientist to lead the design, execution, and scientific oversight of first-in-human trials. You will partner across Clinical Development, Operations, Translational Science, Regulatory, Biometrics and Safety to shape study strategy and cross-functional execution.

You will develop and author clinical/regulatory documents, review emerging data, guide dose-escalation decisions, and help build

Qualifications

• PhD, PharmD, MD, or equivalent advanced scientific degree required.
• 8+ years of clinical research or development in biotech/pharma.
• Strong background in hematology/oncology with Phase 1/FIH experience.

Responsibilities

• Lead as the primary Clinical Scientist on Phase 1 FIH hematologic trials.
• Define study design, dose-escalation strategies, and data interpretation.
• Develop and review protocols, amendments, IBs, SAP shells, and regulatory materials.
• Provide scientific leadership in governance meetings and cross-functional forums.
• Support regulatory submissions, abstracts, posters, and publications.

Skills

Clinical leadership

Cross-functional leadership

Data interpretation

Regulatory writing

Scientific communication

Biotech/Pharma experience

Phase 1 expertise

Hematology/Oncology

Education

PhD/MD/ PharmD or equivalent

Tools

Job description

Damora Therapeutics in Waltham, MA and San Francisco, CA is seeking a Director/Senior Director, Clinical Scientist to lead the design, execution, and scientific oversight of first-in-human trials. You will partner across Clinical Development, Operations, Translational Science, Regulatory, Biometrics and Safety to shape study strategy and cross-functional execution.

You will develop and author clinical/regulatory documents, review emerging data, guide dose-escalation decisions, and help build