Senior Director, Biostatistics — Lead Strategic Clinical Stats

Rhythm Pharmaceuticals Inc.; Boston (MA); Hybrid; USD 210,000 - 300,000; Full time

Job summary

Rhythm Pharmaceuticals Inc. in Boston, MA, seeks a Senior Director of Biostatistics to lead statistical strategy for pivotal clinical programs and partner across clinical, regulatory, safety, data management, and medical writing teams.

The ideal candidate holds a PhD in statistics, 10+ years of biostatistics experience in pharma/biotech, and expertise with SAS, R, and CDISC standards; strong communication and leadership are essential in our hybrid work environment.

Qualifications

• PhD in statistics, biostatistics, or related quantitative field preferred.
• 10+ years biostatistics experience in pharma/biotech.
• Proficient in SAS and R; CDISC SDTM/ADaM knowledge.

Responsibilities

• Serve as lead statistician for assigned programs; shape strategy and analyses.
• Collaborate with cross-functional teams to integrate statistics into plans.
• Prepare statistical content for regulatory documents (SSPs, SDs, reports).
• Oversee vendors and ensure high-quality deliverables.
• Review efficacy and safety analyses with programming teams.
• Support interim analyses and regulatory submissions; contribute to publications.

Skills

PhD in statistics

Biostatistics experience

SAS and R

CDISC SDTM/ADaM

Project leadership

Communication skills

Education

PhD in Statistics

Tools

SAS

R

EAST

Job description

Rhythm Pharmaceuticals Inc. in Boston, MA, seeks a Senior Director of Biostatistics to lead statistical strategy for pivotal clinical programs and partner across clinical, regulatory, safety, data management, and medical writing teams.

The ideal candidate holds a PhD in statistics, 10+ years of biostatistics experience in pharma/biotech, and expertise with SAS, R, and CDISC standards; strong communication and leadership are essential in our hybrid work environment.