Senior Director Analytical Sciences & GMP Partnerships

ORIC Pharmaceuticals Inc.; San Diego (CA); Hybrid; USD 170,000 - 185,000; Full time

Job summary

ORIC Pharmaceuticals Inc. is seeking an experienced analytical R&D scientist to lead analytical method development, validation, and QA‑driven drug development activities in a hybrid setting at our San Diego campus.

You will work on outsourced and in‑house programs, providing technical guidance to CDMOs/CTOs, and collaborating with Regulatory, Quality, and Clinical teams to drive IND/NDA readiness and robust control strategies.

Qualifications

• Ph.D. in analytical chemistry with 7-10+ years of pharma/biotech experience.
• Proven problem-solving, curiosity, and adaptability in a fast-paced setting.
• Strong initiative, ownership and strategic input in drug development programs.
• Experience in process chemistry to build control strategies and NDA readiness.
• Hands-on expertise with analytical technologies (UHPLC, GC, LC-MS, SFC, DSC/TGA).
• PIP oversight and experience in late-stage/ comercial context preferred.
• Knowledge of cross-functional activities such as toxicology and clinical development.
• Working in GLP and cGMP environments with strong documentation discipline.

Responsibilities

• Lead and oversee analytical method development, validation, and release at CDMOs and in-house.
• Drive solid-state characterization, stability testing, and data review across programs.
• Develop specifications for RP/IPC/ intermediates and APIs using historical batch data.
• Guide investigations and quality events with quality teams and regulators when needed.
• Prepare and review technical reports, data packages, and NDA support materials.
• Communicate results clearly to management and cross-functional partners.
• Ensure batch genealogy, stability data, and test results are archived and accessible.

Skills

UHPLC

GC

LC-MS

SFC

Dissolution

DSC/TGA

XRPD

PIP oversight

Regulatory filings

Education

PhD in Analytical Chemistry

Tools

UHPLC Systems

GC Systems

LC-MS Instruments

SFC Equipment

Method Validation

ICH Guidelines

Job description

ORIC Pharmaceuticals Inc. is seeking an experienced analytical R&D scientist to lead analytical method development, validation, and QA‑driven drug development activities in a hybrid setting at our San Diego campus.

You will work on outsourced and in‑house programs, providing technical guidance to CDMOs/CTOs, and collaborating with Regulatory, Quality, and Clinical teams to drive IND/NDA readiness and robust control strategies.