Senior Computational Biologist & Biomarker Analytics Lead

BioSpace; South San Francisco (CA); On-site; USD 182,000 - 247,000; Full time

Benefits offered by this job

Retirement plan

Medical, dental and vision coverage

Stock-based incentives

Flexible work models

Job summary

Amgen seeks a highly motivated Associate Director of Computational Biology in South San Francisco to advance clinical programs through biomarker data analysis and integration of multi-omics with clinical metadata.

The role requires leadership in matrixed teams, expert statistical modeling, and collaboration with clinical scientists to deliver insights for precision medicine and drug development.

Qualifications

• PhD in Bioinformatics, Mathematics, Computer Science, Computational Biology or Data Science is preferred.
• Strong background in cardiovascular/metabolic diseases is highly valued.
• Hands-on experience in statistical modeling, machine learning, and AI for clinical biomarker data.
• Proficiency in R and Python for data manipulation and visualization.

Responsibilities

• Develop biomarker analysis plans to support precision medicine and evidence generation.
• Define workflows for biomarker data analysis integrating multi-omics and clinical data.
• Lead analysis of clinical biomarker data across multiple platforms.
• Support target engagement evaluation and patient stratification.
• Collaborate with cross-functional teams to integrate insights into translational analytics.

Skills

Python

R

Statistics

Data analysis

Leadership

Machine learning

Education

PhD in Bioinformatics/Math/CS/Computational Biology/Data Science

Masters degree

Bachelors degree

Tools

Python

R programming

Job description

Amgen seeks a highly motivated Associate Director of Computational Biology in South San Francisco to advance clinical programs through biomarker data analysis and integration of multi-omics with clinical metadata.

The role requires leadership in matrixed teams, expert statistical modeling, and collaboration with clinical scientists to deliver insights for precision medicine and drug development.