Senior Clinical Trial Manager — Remote Global Leader

NCBioImpact; Durham (NC); Remote; USD 112,000 - 222,000; Full time

Job summary

Worldwide Clinical Trials is seeking a Senior Clinical Trial Manager to lead site management across the full trial lifecycle, partnering with sponsors, CRAs, and cross-functional project teams to ensure high-quality outcomes. This is a remote role in the United States with travel up to 25%.

You will oversee monitoring activities, drive collaboration, and guide teams to successful study execution in a patient-focused, compliant environment.

Qualifications

• Bachelor’s or nursing degree required; clinical trial management experience.
• 4+ years of CRA experience.
• Ability to travel up to 25%.
• Experience supporting Internal Medicine clinical trials (IMID, Cardio Metabolic, Rare Disease).
• Ability to lead remote teams.

Responsibilities

• Lead clinical site management activities throughout the full study lifecycle.
• Serve as primary Site Management representative for monitoring and site activities across assigned projects.
• Act as sponsor-facing contact, building partnerships and ensuring effective communication.
• Oversee monitoring deliverables to meet study objectives, quality, and budget.
• Identify and manage out-of-scope activities with proactive communication.
• Drive collaboration across cross-functional teams to ensure consistent execution.
• Provide leadership and operational oversight to project teams.

Skills

Site management leadership

Sponsor-facing liaison

Monitoring oversight

Cross-functional collaboration

Education

Bachelor's or Nursing degree

Job description

Worldwide Clinical Trials is seeking a Senior Clinical Trial Manager to lead site management across the full trial lifecycle, partnering with sponsors, CRAs, and cross-functional project teams to ensure high-quality outcomes. This is a remote role in the United States with travel up to 25%.

You will oversee monitoring activities, drive collaboration, and guide teams to successful study execution in a patient-focused, compliant environment.