Senior Clinical Trial Manager, Oncology Operations

Revolution Medicines; San Francisco (CA); On-site; USD 120,000 - 150,000; Full time

Job summary

Revolution Medicines seeks an experienced Clinical Trial Manager of Clinical Operations for on-site work in Redwood City, CA. The role oversees CROs, manages trial execution and TMF, and ensures trials comply with GCP and FDA requirements.

Oncology experience is preferred, with strong cross-functional collaboration and leadership skills. The successful candidate will lead vendor management, monitor study progress, and contribute to safety and study reports, while traveling up to ~25% as needed

Qualifications

• BS or MS degree in life sciences with at least 5 years in clinical operations, preferably oncology drug development.
• Excellent written and verbal communication skills.
• Ability to travel around 25% of the time.
• Experience in managing CROs/vendors and external resources.

Responsibilities

• Oversee CROs and vendors to ensure trials are on time, on budget, and compliant with SOPs, FDA regulations, ICH/GCP.
• Review and contribute to study documentation (protocols, CRFs, manuals, informed consent forms).
• Manage TMF documentation and ensure proper trial master file filing.
• Monitor data quality and trial progress; escalate issues as needed.
• Collaborate with cross-functional teams (Clinical Development, Regulatory, QA, Finance, Legal).
• Lead enrollment forecasting vs actuals and assist with budgets and contracts.

Skills

Communication skills

Multi-tasking

Team collaboration

Travel readiness

Oncology drug development knowledge

Education

BS or MS degree in life sciences

5+ years clinical operations experience

Job description

Revolution Medicines seeks an experienced Clinical Trial Manager of Clinical Operations for on-site work in Redwood City, CA. The role oversees CROs, manages trial execution and TMF, and ensures trials comply with GCP and FDA requirements.

Oncology experience is preferred, with strong cross-functional collaboration and leadership skills. The successful candidate will lead vendor management, monitor study progress, and contribute to safety and study reports, while traveling up to ~25% as needed