Senior Clinical Trial Leader, Global Portfolio

NURIX; San Francisco (CA); On-site; USD 182,000 - 194,000; Full time

Job summary

Nurix Therapeutics is seeking a Senior Clinical Trial Manager (Sr. CTM) to lead a portfolio of trials or a full geographic region from Brisbane, CA.

This role involves shaping protocol strategy, driving vendor/CRO relationships, and ensuring program-wide success in a fast-paced biotech environment. Ideal candidates bring 8–10+ years in clinical operations, strong regulatory knowledge (FDA/EMA/ICH/GCP), and a proven track record mentoring CTMs/CTAs.

Qualifications

• S./B.A. in biological sciences with 8-10+ years of relevant industry experience.
• Ability to travel as required for the program (25%).
• Deep working knowledge of FDA, EMA, ICH, and GCP regulations and guidelines.
• Proven experience managing global trials or multi-region programs.
• Track record leading vendor/CRO relationships at a strategic level.
• Experience mentoring or developing junior CTMs/CTAs.
• Strong executive presence and ability to influence without direct authority.
• Comfortable operating with minimal oversight and setting direction for others.
• Outstanding organizational skills and ability to manage multiple trials.
• Thrives in a fast-paced, small-company environment.

Responsibilities

• Own operational strategy across multiple clinical trials and/or a full geographic region.
• Shape protocol strategy and provide senior input on study design and data collection approach.
• Lead vendor/CRO selection strategy and own contract negotiation leverage across trials.
• Serve as the escalation point for vendor or site issues CTMs can’t resolve.
• Own program-level budget forecasting and proactively flag financial risk across the portfolio.
• Mentor and develop CTMs and CTAs, providing hands-on guidance and informal supervision.
• Lead audit readiness strategy and serve as the point person across multiple trials during inspections.
• Represent Clinical Operations at the program or franchise level, and represent Nurix externally at professional events.
• Anticipate risk across the trial portfolio and shape process or strategy to prevent issues.
• Lead cross-functional strategic initiatives rather than simply participating in them.

Skills

Executive presence

Mentoring experience

Organizational skills

Global trials experience

Vendor/CRO relationship management

Regulatory knowledge (FDA/EMA/ICH/GCP)

Education

B.S. in biological sciences

Job description

Nurix Therapeutics is seeking a Senior Clinical Trial Manager (Sr. CTM) to lead a portfolio of trials or a full geographic region from Brisbane, CA.

This role involves shaping protocol strategy, driving vendor/CRO relationships, and ensuring program-wide success in a fast-paced biotech environment. Ideal candidates bring 8–10+ years in clinical operations, strong regulatory knowledge (FDA/EMA/ICH/GCP), and a proven track record mentoring CTMs/CTAs.