Senior Clinical Operations Lead – Remote Oncology Trials

Immatics US, Inc.; Houston (TX); On-site; USD 165,000 - 180,000; Full time

Benefits offered by this job

Health, dental & vision

Vacation 4 weeks

Holidays 12

Sick leave 7 days

401(k) with company match

Life insurance

Disability coverage

Parental leave

Job summary

Immatics US, Inc. is seeking a Principal Manager, Clinical Operations Lead to oversee US regional clinical trials in our cancer immunotherapy programs. This remote role reports to the Associate Director, Clinical Asset Management and guides CTMs, CRAs and CTAs across studies.

Enjoy a comprehensive benefits package and a leadership role shaping end-to-end trial delivery, vendor management, risk mitigation, and cross-functional collaboration in a fast-paced biotech environment.

Qualifications

• Bachelor’s degree in life science, nursing, or similar.
• 7+ years of leadership in global clinical operations with trial oversight and vendor management.

Responsibilities

• Lead trial execution and operational delivery across internal and external stakeholders.
• Oversee CROs and vendors to meet quality, timelines and budget.
• Direct the Clinical Operations team for each project.
• Identify risks and plan mitigations across studies.
• Support study start-up, site feasibility, enrollment and execution.
• Collaborate with Regulatory, Safety, Biometrics, Supply Chain and leadership.

Skills

Leadership

Global clinical ops

Vendor management

Cross-functional leadership

Study leadership

CTM/CRA/CTA oversight

Budget management

Education

Bachelor's degree in life science or nursing

Master's degree preferred

Job description

Immatics US, Inc. is seeking a Principal Manager, Clinical Operations Lead to oversee US regional clinical trials in our cancer immunotherapy programs. This remote role reports to the Associate Director, Clinical Asset Management and guides CTMs, CRAs and CTAs across studies.

Enjoy a comprehensive benefits package and a leadership role shaping end-to-end trial delivery, vendor management, risk mitigation, and cross-functional collaboration in a fast-paced biotech environment.