Remote Senior Clinical Operations Lead - Oncology

Immatics; Houston (TX); On-site; USD 165,000 - 180,000; Full time

Benefits offered by this job

Health insurance

Vacation

Paid holidays

Sick time

Life insurance

Disability insurance

401(k) match

Parental leave

Voluntary benefits

Job summary

Immatics is seeking a Principal Manager, Clinical Operations Lead to oversee US regional clinical trials within our development programs. You will manage trial delivery from start-up through execution, coordinating internal teams and external CROs to meet quality, timelines, and budget goals.

Reporting to the Associate Director, Clinical Asset Management, this role is US-based with a fully remote setup. Salary ranges from $165,000 to $180,000, reflecting senior leadership and oncology experience

Qualifications

• Bachelor’s degree in life science, nursing, or similar.
• 7+ years of global clinical operations leadership including trial oversight, vendor management, and cross-functional study leadership.
• Noted experience in late phase or launch in oncology.
• Experience cell and/or gene therapy, or other complex biologic clinical development programs.

Responsibilities

• Lead clinical trial execution and operational delivery across internal and external stakeholders from study start-up through execution.
• Provide oversight of CROs, vendors, and clinical trial partners to ensure quality, compliance, timelines, and budget objectives are achieved.
• Serve as the Clinical Operations leader for the team of CTMs, CRAs and CTAs for each assigned project.
• Drive risk identification, issue escalation, and mitigation planning across assigned studies.
• Support study start up, site feasibility, enrollment, and operational execution activities.
• Partner cross-functionally with Clinical Development, Regulatory, Safety, Biometrics, Supply Chain, Program Leadership and external vendors.
• Contribute to SOP development, process optimization, inspection readiness, and operational excellence initiatives.
• Mentor and coach junior Clinical Operations team members as applicable.

Skills

Leadership

Global clinical operations

Vendor management

Cross-functional leadership

Education

Bachelor's degree in life science, nursing, or similar

Master’s Degree in life science or nursing

Job description

Immatics is seeking a Principal Manager, Clinical Operations Lead to oversee US regional clinical trials within our development programs. You will manage trial delivery from start-up through execution, coordinating internal teams and external CROs to meet quality, timelines, and budget goals.

Reporting to the Associate Director, Clinical Asset Management, this role is US-based with a fully remote setup. Salary ranges from $165,000 to $180,000, reflecting senior leadership and oncology experience