Senior Biologics Separation Sciences Associate

Takeda; Lexington (VA); On-site; USD 90,000 - 141,000; Full time

Job summary

Takeda in Lexington, MA is seeking a Senior Research Associate in Analytical Development–Separation Sciences. You will independently design, execute, and document separation-based experiments for biologics, including monoclonal antibodies and other therapeutic proteins, using SEC-HPLC, IEX-HPLC, RP-HPLC, HIC-HPLC, UPLC, CE-SDS, icIEF, and cIEF.

You will collaborate with Process Development, Quality, Regulatory, and Manufacturing Sciences to generate high-quality data, troubleshoot issues, and

Qualifications

• Associate degree with 4+ years, bachelor’s degree with 2+ years, or master’s degree with 0+ years of relevant industry experience in analytical chemistry, biochemistry, protein chemistry, biologics analytical development, quality control, or a related discipline.
• Previous hands-on experience working in a laboratory setting is required.
• Experience with separation-based analytical methods for biologics, proteins, peptides, or related complex molecules.

Responsibilities

• Independently design, plan, execute, analyze, and document routine, moderately complex, and selected advanced separation sciences experiments under general direction.
• Perform analytical and biophysical studies to assess biologics structure, heterogeneity, purity, stability, degradation pathways, and product-related variants.
• Apply methods such as SEC-HPLC, IEX-HPLC, RP-HPLC, HIC-HPLC, UPLC, CE-SDS, icIEF, cIEF, glycan analysis, and related separation-based techniques.
• Support method development, method optimization, qualification, validation, transfer, troubleshooting, lifecycle management, and QC readiness activities.
• Prepare and review experimental protocols, laboratory records, technical reports, data summaries, method documents, SOPs, and technology transfer documentation.

Skills

Analytical chemistry

Biochemistry

Biologics analytics

Laboratory techniques

Education

Associate degree

Bachelor’s degree

Master’s degree

Tools

SEC-HPLC

IEX-HPLC

RP-HPLC

HIC-HPLC

UPLC

CE-SDS

icIEF

cIEF

glycan analysis

LIMS

Job description

Takeda in Lexington, MA is seeking a Senior Research Associate in Analytical Development–Separation Sciences. You will independently design, execute, and document separation-based experiments for biologics, including monoclonal antibodies and other therapeutic proteins, using SEC-HPLC, IEX-HPLC, RP-HPLC, HIC-HPLC, UPLC, CE-SDS, icIEF, and cIEF.

You will collaborate with Process Development, Quality, Regulatory, and Manufacturing Sciences to generate high-quality data, troubleshoot issues, and