Senior Bioinformatics Scientist - Clinical Diagnostics

Roche; Pleasanton (CA); On-site; USD 102,000 - 168,000; Full time

Job summary

Roche Diagnostics seeks a Senior Bioinformatics Scientist to advance molecular assay development across NGS, Nanopore sequencing, and PCR. You will design, implement, and maintain analytical tools and workflows, collaborating with bioinformaticians, wet-lab scientists, and external customers to deliver robust diagnostics software for patient care.

You will ensure data quality, reproducibility, and scalable analyses, while contributing to cancer biology knowledge and regulatory-ready workflows in

Qualifications

• Bachelor's degree and 7+ years of experience.
• PhD with 2 years of industry experience in clinical diagnostics or related domain or Masters with 5 years of industry experience.
• Expertise in DNA/RNA sequencing data analysis and interpretation.
• Strong understanding of molecular biology and NGS laboratory processes.

Responsibilities

• Design, implement, and maintain internal algorithms and tools for clinical diagnostic assay development.
• Develop and maintain analytical tools and pipelines for processing diagnostic data from tumor, germline, and cell-free DNA samples.
• Create, implement, and streamline bioinformatics tools and workflows in partnership with wet lab scientists.
• Troubleshoot to ensure data quality, integrity, and accessibility across the diagnostic workflow.
• Advocate for best practices in documenting, training, and scaling algorithms, tools, and workflows to ensure reproducibility and scalability.
• Communicate project outcomes and team progress across various teams and organizational functions.

Skills

DNA/RNA sequencing data analysis

Bioinformatics

Programming in Python/R

Linux environment

Data visualization

Workflow management

Education

Bachelor's degree

PhD in Bioinformatics/Computational Biology/Statistics

Master's in Bioinformatics/Computational Biology/Statistics

Tools

Snakemake

Nextflow

R

Python

Job description

Roche Diagnostics seeks a Senior Bioinformatics Scientist to advance molecular assay development across NGS, Nanopore sequencing, and PCR. You will design, implement, and maintain analytical tools and workflows, collaborating with bioinformaticians, wet-lab scientists, and external customers to deliver robust diagnostics software for patient care.

You will ensure data quality, reproducibility, and scalable analyses, while contributing to cancer biology knowledge and regulatory-ready workflows in