Lead Bioinformatics Scientist, AI-Driven Diagnostics

Roche; Santa Clara (CA); On-site; USD 121,000 - 225,000; Full time

Job summary

Roche in Santa Clara, CA seeks a Bioinformatics Scientist to design and optimize NGS data pipelines and validation studies. You will bridge wet-lab innovation with production-grade software, leveraging AI tools to accelerate development and deliver accurate diagnostic insights.

The role entails collaborating across assay development, software engineering, and quality teams to ensure robust, compliant clinical software and scalable pipelines.

Qualifications

• Bachelor’s or higher in a relevant field with substantial related experience.
• Experience in CAP/CLIA-certified lab environments is a plus.
• Strong programming and statistical analysis skills for sequencing data.
• Familiarity with high-throughput sequencing data and diagnostic workflows.

Responsibilities

• Design, optimize, and validate NGS data processing pipelines and algorithms.
• Act as bridge between wet-lab innovation and production-grade software.
• Integrate AI coding tools to accelerate development and analysis.
• Draft specs to guide software engineers in turning research into clinical tools.
• Maintain QC metrics and thorough documentation for audits.

Skills

Python

R

C++

Linux/Bash

Education

Advanced degree in relevant field

Tools

Nextflow

Docker

Singularity

Cloud environments

Git

CI/CD

Job description

Roche in Santa Clara, CA seeks a Bioinformatics Scientist to design and optimize NGS data pipelines and validation studies. You will bridge wet-lab innovation with production-grade software, leveraging AI tools to accelerate development and deliver accurate diagnostic insights.

The role entails collaborating across assay development, software engineering, and quality teams to ensure robust, compliant clinical software and scalable pipelines.