Senior Associate Scientist - CAR T Molecular Analytics & ddPCR

Bristol-Myers Squibb Company; Seattle (WA); On-site; USD 103,000 - 124,000; Full time

Benefits offered by this job

Flexible Time Off

11 paid holidays

Global Shutdown

Job summary

Bristol Myers Squibb in Seattle, WA seeks a Senior Associate Scientist to join the BioEngineering & Technology Innovation team in the Cell Therapy Research Thematic Research Center. You will develop and run engineered CAR T-cell assays, focusing on ddPCR/qPCR to assess gene editing in Cell Therapy products.

The role requires hands-on molecular biology work, nucleic acid extraction, data analysis, and collaboration with senior researchers to meet project goals in a fast-paced environment.

Qualifications

• Bachelor’s Degree or Master’s with appropriate bioscience experience.
• 4+ years of academic and/or industry experience (Bachelor’s track).
• 2+ years of academic and/or industry experience (Master’s track).
• Hands-on experience developing and running ddPCR assays, including primer/probe design and optimization, ideally for measuring gene-editing outcomes.
• Experience with nucleic acid extraction and characterization.
• Understanding of gene-editing technologies (CRISPR/Cas, base editing) and outcomes.

Responsibilities

• Develop, optimize, and run custom ddPCR assays to measure gene-editing outcomes in Cell Therapy products.
• Perform qPCR and ddPCR workflows on gene-edited samples and refine analytical approaches.
• Extract, clean up, and assess quality of nucleic acids from primary cells and cell lines.
• Optimize PCR parameters for targeted analyses.
• Design and execute experiments, analyze results, and communicate findings to inform decisions.
• Coordinate and collaborate with cross-functional teams to deliver molecular analytical methods for cell therapy.

Skills

ddPCR/qPCR hands-on

nucleic acid extraction

cell culture

data analysis in Excel

labs & documentation

collaboration

experimental design

Education

Bachelor’s degree

Master’s degree

Tools

ddPCR/qPCR platforms

QX200/QXOne/CFX Maestro

nucleic acid extraction kits

Leprechaun imaging platform

Job description

Bristol Myers Squibb in Seattle, WA seeks a Senior Associate Scientist to join the BioEngineering & Technology Innovation team in the Cell Therapy Research Thematic Research Center. You will develop and run engineered CAR T-cell assays, focusing on ddPCR/qPCR to assess gene editing in Cell Therapy products.

The role requires hands-on molecular biology work, nucleic acid extraction, data analysis, and collaboration with senior researchers to meet project goals in a fast-paced environment.