Senior ADME Scientist: Automation & AI Analytics

Novartis; Cambridge (MA); On-site; USD 90,000 - 183,000; Full time

Benefits offered by this job

Health insurance

Life insurance

Disability benefits

401(k) with company match

Generous PTO

Job summary

Novartis in Cambridge, MA is seeking a Senior Scientist I/II to support discovery and development through ADME assays, build next-generation lab automation, and deliver high-quality data for decision-making.

The role involves planning and executing ADME workflows, advancing automated methods, and contributing to cross-functional teams, with competitive compensation and comprehensive benefits.

Qualifications

• BSc or MSc with relevant experience in drug metabolism and pharmacokinetics.
• BSc: 7+ years; MSc: 4+ years of ADME/DMPK experience. Senior Scientist II level possible.
• Experience in drug discovery or development labs or CRO/Pharma/Biotech preferred.
• Experience with metabolic stability and permeability assays; cell culture a plus.
• Automation integrated with AI-enabled analytics is desirable.

Responsibilities

• Plan, execute and report ADME assays such as metabolic stability and permeability.
• Interpret in vitro ADME data to support discovery and compound optimization.
• Advance automation strategies to expand capacity and standardize execution.
• Deliver fully automated ADME workflows integrated with AI analytics.
• Develop methods for LCMS-MS, HRMS, and ICP-MS bio-analysis.
• Troubleshoot lab instrumentation and automation platforms.
• Manage study timelines, objectives and budgets; track progress.
• Communicate data and strategy to project teams; contribute to reports.
• Participate in cross-department initiatives; complete trainings.

Skills

ADME assays

Automation

LCMS/HRMS/ICP-MS

Education

BSc in relevant field

MSc in relevant field

Tools

Automation platforms

Job description

Novartis in Cambridge, MA is seeking a Senior Scientist I/II to support discovery and development through ADME assays, build next-generation lab automation, and deliver high-quality data for decision-making.

The role involves planning and executing ADME workflows, advancing automated methods, and contributing to cross-functional teams, with competitive compensation and comprehensive benefits.