Scientist, Viral Delivery & AAV Vector Engineering

Regeneron Pharmaceuticals; Tarrytown (GA); On-site; USD 94,000 - 153,000; Full time

Job summary

Regeneron Pharmaceuticals in Tarrytown, NY, seeks a Scientist to join the Viral Delivery Technologies group to develop an antibody-retargeted AAV screening platform. You will design, validate, and optimize vectors, and work with cross-functional teams to advance gene therapy delivery solutions.

The role emphasizes in vitro/in vivo experimentation, molecular biology techniques, and advanced sequencing workflows, with onsite work and regular project updates across research teams.

Qualifications

• 8+ years relevant industry or academic experience with BA/BS, or 6+ years with MS
• NGS library prep, optimization, troubleshooting, and QC experience
• Strong molecular biology experience including DNA isolation, PCR, and cloning
• Mammalian cell culture and manipulation; purification of viruses/proteins
• Excellent presentation and communication skills
• Familiar with software tools (Office, GraphPad Prism, Benchling, MacVector)

Responsibilities

• Design, execute, analyze, and troubleshoot in vitro and in vivo experiments to characterize antibody-retargeted viral vector designs and screening protocols
• Apply molecular biology techniques including cloning, SDS-PAGE, Western blotting, DNA/RNA extraction, PCR, RT-PCR, ddPCR, and qPCR
• Design AAV genomes and perform recombinant AAV production to inform vector optimizations
• Develop and optimize NGS library preparation workflows for screening and characterization
• Collaborate with bioinformatics to analyze large NGS datasets
• Prepare regular updates and presentations for team and department forums
• thrive in a fast-paced, collaborative environment with attention to detail while juggling multiple projects

Skills

NGS proficiency

Molecular biology

Mammalian cell culture

Communication skills

Team collaboration

Education

BA/BS + 8+ years

MS + 6+ years

Tools

Microsoft Office

GraphPad Prism

Benchling

MacVector

Job description

Regeneron Pharmaceuticals in Tarrytown, NY, seeks a Scientist to join the Viral Delivery Technologies group to develop an antibody-retargeted AAV screening platform. You will design, validate, and optimize vectors, and work with cross-functional teams to advance gene therapy delivery solutions.

The role emphasizes in vitro/in vivo experimentation, molecular biology techniques, and advanced sequencing workflows, with onsite work and regular project updates across research teams.