Scientist, Immunology and Non-viral engineering

MaxCyte; Rockville, Northern (MD, KY); On-site; USD 120,000 - 170,000; Full time

Benefits offered by this job

Base salary, annual bonus, and equity

Comprehensive benefits (health, dental

Vision, life, and disability insurance

Job summary

MaxCyte is seeking a Scientist, Immunology & Non-viral Engineering in Rockville, MD, to develop non-viral gene editing workflows and advance immune cell engineering using electroporation technology. You will work across immunology and molecular biology, driving high-quality data for internal R&D, customer collaborations, and platform innovation.

The role requires hands-on experience with CRISPR/Cas systems, RNPs, mRNA or DNA templates, and strong flow cytometry skills.

Qualifications

• PhD with 2–3+ years hands-on non-viral gene editing experience.
• Strong immune cell biology background and flow cytometry proficiency.
• Experience with CRISPR/Cas RNPs, mRNA, or DNA delivery.
• Experience in high-throughput screening and automation.

Responsibilities

• Design and execute non-viral gene editing workflows using CRISPR/Cas systems, RNPs, mRNA, and DNA templates.
• Engineer primary human immune cells (T cells, NK cells, macrophages) and assess editing efficiency, viability, and function.
• Perform activation, proliferation, cytokine profiling, cytotoxicity, and phenotyping assays.
• Analyze flow cytometry, NGS, and molecular data and summarize for teams and partners.
• Apply MaxCyte’s non-viral delivery tech to optimize workflows and troubleshoot.
• Design, perform, and troubleshoot experiments per protocols and standards.
• Prepare technical summaries and present results to stakeholders.
• Collaborate with project management to align and deliver materials.
• Provide scientific support to customer-facing teams, including troubleshooting.
• Evaluate new technologies and automation to increase efficiency.
• Contribute to internal innovation and platform enhancements.
• Maintain accurate, compliant lab records and adhere to safety standards.

Skills

CRISPR/Cas editing

Flow cytometry

High-throughput screening

Automation tools

Scientific collaboration

Scientific communication

Education

PhD in Immunology, Molecular Biology, or related

Master’s with 5+ years hands-on non-viral editing

Tools

Electroporation delivery

NGS data analysis

Flow cytometer operation

Job description

Description

The Scientist, Immunology & Non-viral engineering will support MaxCyte’s mission by developing and executing non-viral engineering workflows for immune cells using the company’s electroporation technology. This role combines immunology expertise with hands-on gene editing experience to generate high-quality data that advances internal R&D programs, customer collaborations, and platform innovation. The scientist will work cross-functionally to ensure scientific rigor, operational excellence, and alignment with MaxCyte’s non-viral engineering capabilities.

• Design and execute non-viral gene editing workflows using CRISPR/Cas systems, RNPs, mRNA, and DNA templates in primary cells and cell lines.
• Engineer primary human immune cells (T cells, NK cells, macrophages) and assess editing efficiency, viability, and functional outcomes.
• Perform activation, proliferation, cytokine profiling, cytotoxicity, and phenotyping assays to characterize engineered cells.
• Analyze flow cytometry, NGS, and molecular assay data; prepare clear summaries for internal teams and external partners.
• Apply deep understanding of MaxCyte’s non-viral delivery technology to optimize workflows and troubleshoot experiments.
• Design, perform, and troubleshoot laboratory experiments in accordance with established protocols, quality standards, and regulatory expectations.
• Analyze and interpret experimental data, prepare technical summaries, and present results to internal and external stakeholders.
• Collaborate with project management teams to ensure alignment and timely delivery of materials.
• Provide scientific support to customer-facing teams, including remote and onsite troubleshooting with Field Application Scientists.
• Evaluate and implement new technologies, automation tools, and high-throughput approaches to increase efficiency and scalability.
• Contribute to internal innovation initiatives, including development of new products, platform enhancements, and scientific capability expansion.
• Maintain accurate, complete, and compliant laboratory records.
• Ensure adherence to organizational, regulatory, and safety standards.

Requirements

• PhD in Immunology, Molecular Biology, Cell Biology, or related field with 2-3+ years or Master’s degree with 5+ years of with hands-on experience with non-viral gene editing, including CRISPR/Cas RNPs, mRNA, or DNA template delivery.
• Strong background in immune cell biology, including isolation, activation.
• Proficiency in flow cytometry, multi-color panel design, and immune phenotyping.
• Hands-on experience with electroporation-based delivery or non-viral delivery of gene editing reagents.
• Hands- on experience with high-throughput screening, automation, or advanced analytical tools.
• Ability to work effectively in a structured, fast-paced, milestone-driven industry or core laboratory environment.
• Hands-on experience with cell therapy development, including CAR-T, TCR, NK, DC or macrophage engineering.
• Familiarity with base editing, prime editing, or emerging non-viral modalities.
• Good communication skills and ability to work collaboratively with internal team members and customers.

MaxCyte offers a base salary, annual bonus, and equity.

• MaxCyte also offers a comprehensive benefits package including health, dental, vision, life, and disability insurance and generous time off.

MaxCyte is an Equal Opportunity Employer.

All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status.