Scientist II, Clinical Pharmacology & Pharmacometrics

Immunome, Inc.; Washington (District of Columbia); On-site; USD 120,000 - 180,000; Full time

Job summary

Immunome, Inc. is seeking a Scientist II in Clinical Pharmacology and Pharmacometrics to design quantitative strategies for oncology assets across preclinical to clinical stages.

You will apply PK/PD modeling and simulation to guide dose selection and development decisions for targeted cancer therapies. You will collaborate with cross-functional teams and CROs, maintain rigorous study records, and contribute to go/no-go decisions through robust pharmacology analyses that inform program timelines

Qualifications

• Extensive oncology quantitative pharmacology and pharmacometrics experience.
• Develop clinical pharmacology strategy for oncology programs.
• Proficiency with PK/PD, PBPK, and pharmacometric modeling and simulation.
• Experience managing clinical pharmacology studies with CROs.
• Ability to inform dose selection and go/no-go decisions.
• Strong communication and cross-functional collaboration.

Responsibilities

• Develop clinical pharmacology and pharmacometrics strategy for assets across stages.
• Apply modeling and simulation to characterize PK/PD and exposure dynamics.
• Collaborate with CROs to conduct and monitor pharmacology studies.
• Maintain study records and align with program timelines.

Skills

Oncology quantitative pharmacology

PK/PD modeling

Pharmacometrics

PBPK

Dose selection

CRO management

Cross-functional collaboration

Communication

Job description

Immunome seeks a Scientist II in Clinical Pharmacology and Pharmacometrics to develop quantitative pharmacology strategy for oncology assets across preclinical and clinical stages. The role involves applying PK/PD modeling and simulation to inform dose selection and development decisions for targeted cancer therapies.

Responsibilities

• Develop clinical pharmacology and pharmacometrics strategy for early-stage and late-stage assets
• Apply modeling and simulation approaches to characterize drug absorption, disposition, and effect dynamics
• Collaborate with preclinical and clinical CROs to conduct and monitor pharmacology studies
• Maintain study records and ensure timely study completion aligned with program timelines

Requirements

• Extensive experience in oncology quantitative pharmacology and pharmacometrics
• Clinical pharmacology strategy development in oncology drug programs
• Proficiency with PK/PD, PBPK, and pharmacometric modeling and simulation
• Experience managing clinical pharmacology studies with CROs
• Knowledge of dose selection and go/no-go decision frameworks
• Strong communication and cross-functional collaboration skills