Oncology Clinical Pharmacology & Pharmacometrics Scientist II

Immunome, Inc.; Bothell (WA); On-site; USD 140,000 - 172,000; Full time

Job summary

Immunome, Inc. in Bothell, WA, is seeking a Scientist II in Clinical Pharmacology & Pharmacometrics to drive PK/PD modeling and pharmacometrics strategy for late-stage and early development assets.

You will work with preclinical and clinical teams to design studies, analyze data, and support regulatory submissions. The role emphasizes translational pharmacology, cross-functional collaboration, and delivering an integrated clinical pharmacology roadmap to support registration and labeling.

Qualifications

• Ph.D. or PharmD in a relevant scientific discipline (clinical pharmacology, pharmacometrics or closely related).
• 0-2+ years' experience in pharmaceutical/biotechnology industry in regulated bioanalytical environment, preferably with multiple modalities.
• Experience in noncompartmental and PBPK analyses and pharmacometric modeling and simulation oversight.
• Knowledge of R, R-shiny, SAS, MATLAB, NONMEM, MONOLIX, PBPK (GastroPlus or Simcyp) or similar modeling software.
• Familiarity with current global clinical pharmacology and pharmacometrics regulatory guidance.

Responsibilities

• Formulate and deliver CP&MS strategy for late-stage and early development assets.
• Apply PK/PD, PBPK and modeling & simulation to characterize drug behavior and inform dose selection.
• Coordinate with CROs and company scientists to conduct pharmacology studies and maintain records.
• Contribute to study design, data analysis, report preparation and regulatory submissions.

Skills

Communication skills

Oncology drug development

Cross-functional collaboration

Education

Ph.D. or PharmD in clinical pharmacology/pharmacometrics

Tools

WINNONLIN

NONMEM

MONOLIX

R / R-shiny

SAS

MATLAB

PBPK modeling (GastroPlus/Simcyp)

Job description

Immunome, Inc. in Bothell, WA, is seeking a Scientist II in Clinical Pharmacology & Pharmacometrics to drive PK/PD modeling and pharmacometrics strategy for late-stage and early development assets.

You will work with preclinical and clinical teams to design studies, analyze data, and support regulatory submissions. The role emphasizes translational pharmacology, cross-functional collaboration, and delivering an integrated clinical pharmacology roadmap to support registration and labeling.