Scientist - II (Associate) - MA

TalentBurst; Boston (MA); On-site; USD 70,000 - 100,000; Full time

Job summary

A leading company in the biopharmaceutical field seeks a Scientist - II for a 12-month contract in Boston. The role focuses on developing and conducting biochemical assays and studies related to small molecule ligands, requiring a strong educational background in biochemistry or biophysics and relevant industry experience.

Qualifications

• Minimum of 1-5 years industry experience required.
• Proficiency in basic biochemical and biophysical techniques needed.
• Experience in assay development and compound profiling preferred.

Responsibilities

• Develop and run quantitative biochemical and biophysical assays.
• Conduct studies to elucidate ligand interaction mechanisms.
• Design and implement screening assays independently.

Skills

Biochemistry

Biophysics

Molecular Biology

Teamwork

Communication

Initiative

Education

BS/BA in Biochemistry, Biophysics or related discipline

MS in Biochemistry, Biophysics or related discipline

Tools

Automated Liquid Handlers

TIBCO Spotfire

Excel

PowerPoint

Job description

Job Title: Scientist - II (Associate) - MA
Location: Boston, MA
Duration: 12 months

This is an exciting opportunity in the Biochemistry and Biophysics Group within the Department of Pharmacology at MRL-Boston. The successful candidate is expected to:

• Develop and/or run quantitative biochemical and biophysical assays to support identification, characterization, and optimization of small molecule ligands from high throughput screening campaigns and medicinal chemistry efforts.
• Conduct biochemical and biophysical studies to elucidate the modes of ligand interaction and mechanisms of action on target proteins.

Quals--
Education Requirement:

• BS/BA degree in biochemistry, biophysics or a related discipline with a minimum of 1-5 years industry experience; or a MS degree in biochemistry, biophysics or a related discipline with 1 or more years of industry experience, preferably with a focus on assay development and compound profiling within a drug discovery environment.

Required Skills:
• Candidate should have basic knowledge of biochemistry, biophysics and molecular biology
• Candidate should have prior experience with basic biochemical and/or biophysical techniques
• Candidate should be highly motivated, driven, and willing to take the initiative to learn new scientific methodologies
• Candidate should be a strong team player
• Candidate should have excellent oral and written communication skills
• Candidate should be comfortable using a PC computer and proficient in Windows-based operating systems and basic applications, such as spreadsheets and databases
• Experience in the use of automated liquid handlers such as Echo, Bravo, Biomek, or Hamilton and data analysis and presentation software such as TIBCO Spotfire, Excel and PowerPoint.

Preferred Attributes:
• Proven ability to independently design, develop and implement biochemical and biophysical screening assays using detection modalities such as: TR-FRET, FP, LC-MS, radiochemical, surface plasmon resonance (BIAcore), fluorescence-based thermal shift (TdF), and/or isothermal titration calorimetry (ITC).
• Hands-on experience performing steady-state and transient-state kinetic experiments to study enzymes and inhibitors.
• Direct experience in recombinant protein expression using bacteria, insect (baculovirus) and/or mammalian cell-based systems and purification using automated chromatographic separation systems.


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About the company

Founded in 2002, TalentBurst is the national leader staffing supplier to large MSP contingent workforce programs. Through our 4 delivery centers in Boston, San Francisco, Miami and Gurgaon, India we support 90 Fortune 500 customers every week filling I...

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