Second-Shift Antibody Purification & Conjugation Scientist

Actalent; Carlsbad (CA); On-site; USD 45,000 - 51,000; Full time

Benefits offered by this job

Medical insurance

401(k) plan

Life Insurance

Disability insurance

HSA

PTO

Job summary

Actalent is seeking a Scientist II to join the Antibody Conjugation team on second shift in Carlsbad, CA. You will purify monoclonal antibodies from hybridoma cultures and assist in producing fluorescently labeled bioconjugates for cell‑signaling research applications.

The ideal candidate has antibody or protein purification experience, chromatography workflows, and GMP‑like lab operations. After training, you will own second‑shift production, document activities, and collaborate with

Qualifications

• Bachelor's degree in biology or related life science field.
• Minimum 2 years of relevant laboratory experience.
• Hands-on experience with protein or antibody purification using chromatography-based methods.
• Experience with FPLC/ÄKTA chromatography systems.
• Experience using spectrophotometers for protein concentration and quality analysis.
• Strong quantitative and laboratory math skills.
• Excellent documentation and record-keeping abilities.
• Troubleshooting skills in lab/manufacturing settings.
• Strong written and verbal communication; able to work independently after training.

Responsibilities

• Purify monoclonal antibodies from hybridoma cultures using affinity chromatography.
• Manage multiple production runs to meet schedules and quality standards.
• Operate and maintain chromatography systems including FPLC/ÄKTA.
• Perform concentration and quality assessments using spectrophotometry.
• Support production of fluorescently labeled bioconjugates for research.
• Prepare reagents and materials for purification and conjugation workflows.
• Document production activities and results accurately.
• Follow safety and quality procedures in all operations.
• Troubleshoot routine chromatography and purification issues; escalate complex concerns.
• Collaborate with team and cross-functional partners to support goals.

Skills

Antibody purification

Protein purification

Chromatography workflows

Laboratory math

Documentation

Troubleshooting

Communication

Education

Bachelor's degree in Biology/Biochemistry/Biotechnology

Tools

FPLC

ÄKTA systems

Job description

Actalent is seeking a Scientist II to join the Antibody Conjugation team on second shift in Carlsbad, CA. You will purify monoclonal antibodies from hybridoma cultures and assist in producing fluorescently labeled bioconjugates for cell‑signaling research applications.

The ideal candidate has antibody or protein purification experience, chromatography workflows, and GMP‑like lab operations. After training, you will own second‑shift production, document activities, and collaborate with