Scientist, Bioanalysis

Scorpion Therapeutics; South San Francisco (CA); On-site; USD 110,000 - 143,000; Full time

Benefits offered by this job

401k

Healthcare coverage

ESPP

Job summary

Scorpion Therapeutics seeks a senior scientist to develop and qualify bioanalytical methods supporting discovery and development of novel therapeutics. You will measure biomarkers, drug concentrations, and anti-drug antibodies, and partner with CROs to optimize and transfer assays.

You will write and review study reports per IND/CTA/BLA/NDA guidelines, analyze data, and present findings to cross-functional teams, contributing to a robust regulatory-ready bioanalytical portfolio.

Qualifications

• Ph.D. in Analytical Chemistry or related field (or MS with 3+ years, or BS with 5+ years in biotech/pharma discovery)
• Hands-on bioanalytical method development, qualification/validation, and sample testing
• Experience with sample prep (protein precipitation, liquid-liquid extraction, SPE), chromatography, and triple-quadrupole MS
• Ligand binding assay experience (ELISA, MSD) preferred
• Familiarity with FDA, EMA, ICH guidance for regulated bioanalysis
• Experience with relevant bioanalytical tools and instrumentation
• Excellent critical thinking, communication, and cross-functional collaboration

Responsibilities

• Develop and qualify bioanalytical methods for discovery and development
• Conduct bioanalytical experiments to advance drug development portfolio
• Develop mass spectrometry methods for oligonucleotides and proteins
• Engage bioanalytical CROs for method optimization and transfer
• Prepare and finalize study reports per regulatory guidelines (IND/CTA/BLA/NDA)
• Analyze, interpret, and present data to project teams

Skills

Bioanalytical methods

Method validation

Sample testing

Ligand binding assays

Cross-functional collaboration

Communication skills

Education

PhD in Analytical Chemistry

MS in related field

BS with industry experience

Tools

Mass spectrometry

LC-MS/MS

Chromatography

Bioanalytical instruments

Job description

Key Accountabilities/Core Job Responsibilities

• Develop and qualify bioanalytical methods supporting discovery and development of novel therapeutics, including measurement of biomarkers, drug concentration, and anti-drug antibodies.
• Conduct bioanalytical experiments to support advancement of the drug development portfolio.
• Work with novel biotherapeutic analyses and contribute to the development of mass spectrometry methods for oligonucleotides & proteins.
• Engage bioanalytical CROs for method optimization, assay transfer, qualification/validation, sample testing, and delivery of results within project timelines.
• Write, review, and finalize bioanalytical study reports adhering to global regulatory guidelines for IND/CTA/BLA/NDA filings.
• Analyze, interpret, and present data to project teams.

Qualifications/Skills

• Ph.D. in Analytical Chemistry, Pharmaceutical Sciences, Biochemistry, or related discipline (or MS with 3+ years, or BS with 5+ years of biotechnology/pharmaceutical discovery and development experience).
• Hands-on experience with bioanalytical method development, qualification/validation, and sample testing.
• Hands-on experience with sample preparation (protein precipitation, liquid-liquid extraction, solid-phase extraction), chromatographic separation, and triple-quadrupole mass spectrometers.
• Ligand binding assay experience (e.g., ELISA, MSD) preferred.
• Practical knowledge of FDA, EMA, and ICH guidance for regulated bioanalysis.
• Experience with relevant bioanalytical tools and instrumentation.
• Excellent critical thinking, communication, and collaboration; experience cross-functionally or with CROs.

Compensation/Benefits

• Salary range: $110,000–$143,000; includes 401k, healthcare coverage, and ESPP.