Senior Scientist I, Analytical Development

Scorpion Therapeutics; Gaithersburg (MD); On-site; USD 114,000 - 182,000; Full time

Benefits offered by this job

Annual bonus

Equity (variable)

Benefits

Job summary

Scorpion Therapeutics is seeking a Senior Scientist I in Analytical Development to lead hands-on laboratory work supporting antibodies and ADC products. You will develop, optimize, and troubleshoot analytical methods, and generate data packages for development and comparability studies.

The role requires a PhD (or MS with extensive industry experience) and a strong track record in biologics CMC and physiochemical characterization.

Qualifications

• PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences or related field with 6+ years relevant experience (post-doc included) or MS with 8+ years industry experience.
• Expertise in analytical development for biopharmaceuticals (antibodies/ADCs).
• Strong background developing physiochemical methods: HPLC, icIEF, CE-SDS; plus extended characterization.
• Working knowledge of biologics CMC expectations, analytical control strategies, and specification support.

Responsibilities

• Perform hands-on laboratory work for analytical method development, optimization, troubleshooting, and phase-appropriate assay support for antibodies and ADCs.
• Generate, analyze, interpret, and document data packages for product development, comparability studies, method transfer readiness, and late-stage program needs.
• Support analytical method lifecycle activities (qualification/validation readiness; assay performance evaluation).
• Contribute to technical documentation (protocols, reports, study summaries, and CMC-related regulatory submission sections).
• Collaborate cross-functionally with internal teams and external partners to improve laboratory execution, data review, and continuous improvement.

Skills

Data analysis

Technical writing

Problem solving

Cross-functional collaboration

Education

PhD in Analytical Chemistry

MS in related field (with 8+ years industry experience)

Tools

HPLC

icIEF

CE-SDS

Job description

About the Role

Senior Scientist I, Analytical Development (hands-on role supporting antibodies and ADC products).

Responsibilities

• Perform hands-on laboratory work for analytical method development, optimization, troubleshooting, and phase-appropriate assay support for antibodies and ADCs.
• Generate, analyze, interpret, and document data packages for product development, comparability studies, method transfer readiness, and late-stage program needs.
• Support analytical method lifecycle activities (qualification/validation readiness; assay performance evaluation).
• Contribute to technical documentation (protocols, reports, study summaries, and CMC-related regulatory submission sections).
• Collaborate cross-functionally with internal teams and external partners to improve laboratory execution, data review, and continuous improvement.

Qualifications

• PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences or related field with 6+ years relevant experience (post-doc included), or MS with 8+ years industry experience.
• Expertise in analytical development for biopharmaceuticals (antibodies/ADCs).
• Strong background developing physiochemical methods: HPLC, icIEF, CE-SDS; plus extended characterization.
• Working knowledge of biologics CMC expectations, analytical control strategies, and specification support.
• Ability to work in cross-functional teams in dynamic environments.
• Strong data analysis, technical writing, problem-solving; willingness to travel domestically/internationally.

Preferred

• BLA-enabling extended characterization experience and late-stage/BLA project experience.

Benefits (selected)

• Expected pay range: $113,600/year to $181,600/year + benefits, annual bonus & equity (variable).