Scientist 3, Immunology

Genentech; South San Francisco (CA); On-site; USD 103,000 - 192,000; Full time

Benefits offered by this job

Relocation benefits

Job summary

Genentech's Immunology Department is seeking a Scientist 3 to investigate novel mechanisms and potential therapeutic targets to treat inflammatory diseases. You will lead projects advancing immune regulation research and contribute to early clinical development.

The role requires strong industry experience in target discovery, independence, and collaboration across labs. You will apply state-of-the-art techniques to test new pathways and determine MOA of targets, with relocation benefits

Qualifications

• PhD with publications in immunology or related field.
• Hands-on experience in cellular and molecular immunology, including primary cell isolation, in vitro assays, flow cytometry, in vivo models.
• Independent design/interpretation of experiments.
• Excellent communication and collaborative skills.
• Ability to present research at internal meetings.

Responsibilities

• Lead projects to investigate novel immunoregulatory mechanisms.
• Advance pipeline programs into early clinical development.
• Provide scientific and technical leadership across immunology labs.
• Generate solid proof-of-concept data to support target discovery.

Skills

Independent experimental design

Excellent communication

Collaborative mindset

Education

PhD in immunology or related field

Tools

Flow cytometry

In vivo animal models

Genome editing (CRISPR)

Job description

The Position

The Opportunity

The Department of Immunology at Genentech is seeking a highly talented, driven and motivated Scientist 3 to investigate novel biological mechanisms and potential therapeutic targets to treat inflammatory diseases. The successful candidate will lead projects that advance our understanding of the cellular and molecular mechanisms of adaptive and innate immunity, with a main emphasis on harnessing immunoregulatory mechanisms for reestablishing immune and tissue homeostasis under inflammatory conditions.

The candidate will be expected to work independently and collaboratively on pipeline projects and will be responsible for advancing exciting and novel research stage programs into early clinical development, providing both scientific and technical expertise and generating solid proof of concept data. Prior industry experience is required, particularly in target discovery. Excellent communication skills, will facilitate fruitful and open collaborations with other labs in immunology, regenerative medicine, human genetics, biomarker discovery and early clinical development. Time and space will be provided to drive both pipeline research and explore new biology and pathways for new target discovery. Using state of the art techniques and technologies, the candidate will have the capacity to develop in vitro and in vivo skills to test the involvement of novel pathways and molecules in the pathogenesis of inflammatory diseases and to identify the mechanism of action (MOA) of new targets.

Who You Are

• PhD degree in immunology, molecular biology, biochemistry or a related field with a demonstrated record of professional achievement in the form of high-quality publications.
• Extensive hands‑on experience in cellular and molecular immunology techniques including primary cell isolation from tissues, in vitro immunological assays, multi-dimensional flow cytometry and in vivo animal models.
• Independently designing, executing and interpreting experiments.
• Have excellent communication skills and willingness to work in a collaborative environment and core lab.
• Can present research at intra- and inter-departmental meetings.

Preferred

• A strong background in adaptive and innate immunity is highly desirable.
• Experience with state-of-the-art precision genome editing technologies and their application for cell engineering is of interest.
• Experience with analysis of data from genomic sequencing, scRNA-seq, TCR-seq, CITE-seq or spatial transcriptomics is a plus.
• Experience with in vivo immunological experimental techniques
• Experience in target discovery within industry research setting

Relocation benefits are available for this posting.

The expected salary range for this position based on the primary location of California is $103,400 to $192,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.