Scientist 2, Translational CVRM

Genentech; San Francisco (CA); On-site; USD 86,000 - 159,000; Full time

Benefits offered by this job

Relocation benefits

Job summary

Genentech’s CVRM Translational Biology group in South San Francisco seeks a motivated scientist to advance cardiometabolic disease research by executing in vivo rodent experiments and analyzing data. You will join a fast-paced, cross-disciplinary team to generate actionable results and guide follow-up studies.

Ideal candidates hold a Bachelor’s in pharmacology/biology or related field (or Master’s with 4+ years) and bring hands-on cardiovascular modeling, rodent handling, and ELN documentation

Qualifications

• Bachelor’s degree in pharmacology, biology, or related fields with 6+ years of lab experience, OR a Master’s with 4+ years in industry or academia.
• Detail-oriented researcher focused on disease modeling to accelerate research.
• Hands-on experience with cardiovascular models and phenotyping; proficient in survival surgical skills.
• Experience with rodent handling and various administration routes (IV, IP, IM, SC); blood sampling and tissue harvest.

Responsibilities

• Establish and conduct experiments in rodent models and optimize disease modeling approaches.
• Generate high-quality data to meet timelines and project goals.
• Communicate findings at project meetings and prioritize follow-up studies.
• Apply scientific knowledge to solve project challenges and stay updated with literature.
• Collaborate within multidisciplinary project teams.
• Maintain accurate ELN records and document complex data for reproducibility.

Skills

In vivo rodent experiments

Cardiovascular modeling

Data analysis

ELN documentation

Team collaboration

Independent work

Education

Bachelor’s degree in pharmacology, biology, or related fields

Master’s degree with 4+ years of experience

Tools

Echocardiography

Heart catheterization

Rodent surgery

Job description

The Position

TheOpportunity

The CVRM (Cardiovascular, Renal, and Metabolism) Translational Biology group within Genentech Research and Early Development (gRED) is seeking a highly motivated and well-trained individual to advance drug discovery research and development efforts by executing in vivo experiments in rodent models of cardiometabolic diseases. This position requires working closely with scientists in a multidisciplinary team. Our environment is exciting and fast paced, requiring you to be excellent at multitasking and easily adaptable to meet evolving goals. This is an exciting opportunity to join a growing CVRM biology group and make significant contributions.

Key Responsibilities:

• Establish and conduct experiments in relevant rodent models and optimize approaches to model disease processes and states which resemble human diseases




• Generate high-quality experimental data to meet strict timelines and project goals.




• Communicate key findings at project meetings and make recommendations for follow-up studies and prioritization.




• Familiar with relevant scientific literature. Understand and apply relevant scientific knowledge to solving problems arising from the projects involved




• Work collaboratively within multidisciplinary project teams




• Generate, analyze, and document complex experimental data with a focus on high reproducibility, maintaining accurate Electronic Lab Notebook (ELN) records.

Who You Are

• Bachelor’s degree in pharmacology, biology, or related fields with 6+ years of laboratory experience, OR a Master’s degree with 4+ years of experience in industry or academia




• A detail-oriented researcher who is passionate about leveraging best disease modeling to accelerate our research and discovery




• Hands-on experience with cardiovascular models (myocardial infarction/ischemia–reperfusion, transverse aortic constriction) and their phenotyping (echocardiography, heart catheterization). Proficient survival surgical skills in rodents




• Experience with rodent handling, various routes of drug administration (intravenous, intraperitoneal, intramuscular and subcutaneous), non-terminal and terminal blood sampling and tissue harvest.




• Strong analytical, organizational and communication skills




• Highly motivated, self-driven person, comfortable working independently or as team in a fast-paced environment




• Willingness to learn new skills and rapidly adapt to changing priorities for multiple projects.

Preferred

• Experience with other cardiometabolic disease models will be a plus.

Relocation benefits are available for this job posting.

The expected salary range for this position based on the primary location of South San Francisco, CA is $85,500 to $158,700. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.