Synthetic DNA Process Development Scientist

Eurofins; Louisville (KY); On-site; USD 70,000 - 95,000; Full time

Benefits offered by this job

Comprehensive medical coverage

401(k) with company match

Paid vacation and holidays

Job summary

Eurofins is seeking a Synthetic DNA Process Development Scientist in Louisville, Kentucky. This full-time role involves designing and optimizing chemical synthesis processes for oligonucleotides and nucleotides. The ideal candidate should hold a Ph.D. or Master’s in Organic Chemistry with a minimum of 5 years of industrial experience in chemical synthesis and oligonucleotide purification process. Excellent benefits are provided including medical, dental, and 401(k) with company match.

Qualifications

• Must have a minimum of 5 years of industrial experience in chemical synthesis.
• Experience with solid-phase oligonucleotide synthesis.
• Experience in oligonucleotide purification process development.

Responsibilities

• Design and optimize chemical synthesis processes for nucleotides and oligonucleotides.
• Troubleshoot synthesis and purification challenges to improve yield and purity.
• Collaborate with manufacturing, QC, and engineering for process transfer.

Skills

Oligonucleotide synthesis expertise

Chemical synthesis process optimization

Strong analytical skills (HPLC, LC-MS)

Education

Ph.D. or Master’s degree in Organic Chemistry

Job description

Synthetic DNA Process Development Scientist

Full-time

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

Eurofins is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. Eurofins is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. The Group also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in‑vitro diagnostic products.

In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to 55,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 50 countries. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

Position Summary

We are seeking a highly skilled and motivated Organic Chemist with expertise in oligonucleotide synthesis and purification to support process development and manufacturing. This role focuses on developing, optimizing, and scaling chemical processes for high‑throughput and high‑quality oligonucleotide production.

Key Responsibilities

• Design, develop, and optimize chemical synthesis processes for nucleotides and oligonucleotides
• Process development and scale‑up from R&D to manufacturing
• Develop and improve oligonucleotide purification processes (e.g., HPLC, ion‑exchange, desalting)
• Troubleshoot synthesis and purification challenges to improve yield and purity
• Collaborate with manufacturing, QC, and engineering for process transfer
• Evaluate new chemistries and technologies
• Author SOPs, batch records, and technical reports
• Ensure compliance with quality systems
• Ph.D. or Master’s degree in Organic Chemistry or related field (required)
• Minimum 5 years of industrial experience in chemical synthesis
• Experience with solid‑phase oligonucleotide synthesis
• Experience in oligonucleotide purification process development
• Strong analytical skills (HPLC, LC-MS)
• Experience scaling processes to manufacturing

Preferred Qualifications

• Experience in GMP or regulated environments
• Familiarity with automated DNA/RNA synthesizers
• Knowledge of modified nucleotides
• Experience in high‑throughput oligo production
• Ability to manage multiple priorities
• Occasional off‑hours support as needed

Schedule

• Monday‑Friday 8:00am-5:00pm

What we offer

• Excellent full time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA Clinical Diagnostics is a Disabled and Veteran Equal Employment Opportunity employer.