Scientist

Aditi Consulting; South San Francisco (CA); On-site; USD 50,000 - 52,000; Full time

Job summary

Aditi Consulting seeks a motivated contract scientist to support multiple therapeutic programs in an intensive, onsite, 12-month role. You will maintain mammalian cell cultures, develop image-based assays, and perform high-content imaging with automated systems.

Collaboration across R&D teams and training of scientists on imaging tools are expected. The position emphasizes quantitative image analysis using platforms like Fiji/ImageJ and Imaris, with preferences for experience in co-culture and

Qualifications

• Strong mammalian cell culture and experimental skills with sterile technique.
• Cell-based assay development and sample preparation; understand impact on data quality.
• Microscopy and quantitative image analysis experience with at least one platform.

Responsibilities

• Maintain mammalian cell cultures and prepare samples for imaging experiments.
• Develop and execute image-based cellular assays and co-culture setups.
• Perform fluorescence microscopy and high-content imaging experiments.
• Collaborate with R&D teams on experimental design, acquisition, and analysis.
• Develop and apply quantitative image analysis workflows using Fiji/ImageJ, Imaris, Harmony, or similar tools.
• Document, interpret, and communicate experimental results.

Skills

Mammalian cell culture

Imaging experiments

Troubleshooting

Education

BS/MS/PhD in biology/biomedical sciences

Tools

Fiji/ImageJ

Imaris

Harmony

CellProfiler

Job description

Payrate

$36.00 - $38.00/hour

Summary

We are seeking a motivated and collaborative contract scientist to support research programs across multiple therapeutic and functional areas. This is a 100% onsite role for 12 months, with potential for extension based on business needs. Preferred schedule is 8:30 AM-5:30 PM.

Job Responsibilities

• Maintain mammalian cell cultures and prepare cells and samples for imaging experiments.
• Develop, optimize, and execute image-based cellular assays, including co-culture and cell-cell interaction assays.
• Perform fluorescence microscopy and automated imaging experiments.
• Support imaging studies conducted in collaboration with scientists across R&D, from experimental design and sample preparation through image acquisition and analysis.
• Develop and apply quantitative image analysis workflows using tools such as Fiji/ImageJ, Imaris, high-content analysis software, or other computational approaches.
• Analyze, interpret, document, and communicate experimental results.
• Contribute to research focused on immune synapses, cell-cell contacts, and other imaging-based approaches relevant to T-cell engager research.
• Assist with operation and routine maintenance of automated high-content imaging instrumentation, including Opera Phenix systems and associated automation.
• Troubleshoot imaging, assay, and sample-preparation issues and work with team members to identify practical solutions.
• Help maintain robust and reproducible imaging workflows, protocols, and documentation.
• Support and, with experience, help train scientists using imaging instrumentation and analysis tools.
• Work collaboratively with imaging scientists, biologists, and project teams across different areas of R&D.
• Learn and adopt new microscopy, automation, assay-development, and image-analysis technologies as needed.

Must Have Skills

• Strong mammalian cell culture and experimental skills, with excellent sterile technique and troubleshooting abilities.
• Experience in cell-based assay development and sample preparation, understanding the impact of variables on assay performance and data quality.
• Microscopy and quantitative image analysis experience, with at least one image analysis platform or approach.

Education and Qualification

• BS, MS, or Ph.D. in cell biology, immunology, bioengineering, biochemistry, biomedical sciences, or a related discipline, with relevant laboratory experience.

Nice to Have Skills

• Experience with primary cells, immune cells, co-culture assays, or cell-cell interaction assays.
• Experience with high-content imaging platforms such as the Opera Phenix.
• Familiarity with automated laboratory workflows, robotic plate handling, or screening environments.
• Familiarity with image analysis tools such as Fiji/ImageJ, Imaris, CellProfiler, Harmony.
• Programming experience in Python, R, MATLAB, or similar environments.

Pay Transparency

The typical base pay for this role across the U.S. is: $36.00 - $38.00/hour. Non-exempt positions are eligible for overtime at a rate of 1.5 times the base hourly rate for all hours worked in excess of 40 in a work week, or as required by state or local law. Final offer amounts, within the base pay set forth above, are determined by factors including your relevant skills, education and experience. Full-time employees are eligible to select from different benefits packages. Packages may include medical, dental, and vision benefits, health savings accounts with qualified medical plan enrollment, 10 paid days off, 3 days paid bereavement leave, 401(k) plan participation with employer match, life and disability insurance, commuter benefits, dependent care flexible spending account, accident insurance, critical illness insurance, hospital indemnity insurance, accommodations and reimbursement for work travel, and discretionary performance or recognition bonus. Sick leave and mobile phone reimbursement provided based on state or local law.