RNA Production Research Associate I

Flagship Pioneering; Cambridge (MA); On-site; USD 43,000 - 62,000; Full time

Job summary

Terrana Biosciences, Cambridge, MA, is seeking a Research Associate I to support IVT RNA production and related molecular biology workflows. You will generate high-quality RNA materials for discovery, platform development, and product advancement across the company.

The role involves DNA assembly, bacterial transformation, IVT, RNA synthesis, QC, and collaboration with Molecular Biology, Discovery, Sequencing, and Bioinformatics teams.

Qualifications

• BS or MS in Molecular Biology, Biochemistry, Biotechnology, Genetics, or a related field.
• RA I: BS degree with up to 2 years of relevant lab experience.
• RA II: BS with 2–4 years or MS with up to 2 years of relevant lab experience.
• Experience with basic molecular biology techniques including PCR, nucleic acid handling, and gel electrophoresis.
• Strong attention to detail, organization, and record-keeping skills.
• Ability to work effectively in a collaborative, fast-paced environment.

Responsibilities

• Execute DNA assembly and molecular cloning workflows to generate constructs for RNA production.
• Perform bacterial transformation, colony screening, plasmid prep, and sequence verification.
• Execute in vitro transcription (IVT) workflows to produce RNA for research programs.
• Perform RNA synthesis, purification, quantification, and QC using established methods.
• Prepare DNA templates, reagents, and materials for IVT production workflows.
• Conduct PCR, gel electrophoresis, and nucleic acid quantification as part of routine biology work.
• Maintain accurate experimental records and track samples using ELab systems.
• Support high-throughput RNA production operations with quality and timely delivery.
• Contribute to workflow optimization, process improvements, and lab organization.
• Collaborate with Molecular Biology, Discovery, Sequencing, and Bioinformatics teams.

Skills

Molecular biology

PCR

Gel electrophoresis

Record-keeping

Team collaboration

Education

BS or MS in Molecular Biology or related field

Tools

LIMS

Automation platforms

Job description

Terrana Biosciences, Cambridge, MA, is seeking a Research Associate I to support IVT RNA production and related molecular biology workflows. You will generate high-quality RNA materials for discovery, platform development, and product advancement across the company.

The role involves DNA assembly, bacterial transformation, IVT, RNA synthesis, QC, and collaboration with Molecular Biology, Discovery, Sequencing, and Bioinformatics teams.