RNA Therapeutics Research Associate

Socket.dev; South San Francisco (CA); On-site; USD 78,000 - 98,000; Full time

Benefits offered by this job

Competitive salary

Equity

Benefits

Job summary

Addition Therapeutics, based in South San Francisco, is seeking a Research Associate for its Therapeutic Technologies team. This hands-on role focuses on producing RNA reagents, running cell-based assays, and generating high-quality data to drive early discovery programs.

The ideal candidate will handle IVT, RNA handling, and mammalian cell culture across multiple cell types, together with cross-functional teams, ensuring data integrity and protocol optimization.

Qualifications

• Bachelor's or Master's degree in molecular biology, biochemistry, cell biology, biotechnology, or a related field, with ~1-2 years of hands‑on laboratory experience (industry preferred).
• Mammalian cell culture skills — sterile technique, maintenance of multiple lines, and transfection.
• Hands‑on molecular biology experience, including RNA handling and RNase‑free technique.
• Demonstrated reliability, organization, and attention to detail — you produce reproducible data and document it clearly.
• Ability to manage multiple concurrent tasks in a fast‑paced environment and to communicate results to a cross‑functional team.

Responsibilities

• Produce research-grade RNA by IVT at routine cadence and scale with purification to defined quality specs.
• Perform RNA QC (concentration, purity, integrity) and keep traceable records for every lot.
• Maintain mammalian cell lines and disease-relevant models for assay readiness.
• Deliver PRINT RNA into cells via transfection, lipofection, and electroporation across cell types.
• Execute readout assays (luciferase, ELISA, qPCR/ddPCR, flow cytometry, microscopy) and generate reproducible data.
• Analyze, plot, and document results in ELN; flag anomalies and help troubleshoot protocols.
• Assist lab operations: inventory, sample tracking, and instrument upkeep.

Skills

RNA handling

Mammalian cell culture

Molecular biology

Attention to detail

Cross-functional communication

Education

Bachelor's or Master's in molecular biology

Tools

qPCR

ELISA

RNA quality control

Job description

Addition Therapeutics, based in South San Francisco, is seeking a Research Associate for its Therapeutic Technologies team. This hands-on role focuses on producing RNA reagents, running cell-based assays, and generating high-quality data to drive early discovery programs.

The ideal candidate will handle IVT, RNA handling, and mammalian cell culture across multiple cell types, together with cross-functional teams, ensuring data integrity and protocol optimization.