Research Technician III - Genetic Neurological Disorders

Baylor College of Medicine; Houston (TX); On-site; USD 48,000 - 62,000; Full time

Job summary

Baylor College of Medicine in Houston seeks a motivated lab assistant to support genetics and molecular neuroscience research, including Alzheimer's, Parkinson's, and MeCP2 projects.

You will perform molecular biology techniques, maintain mouse colonies, collect and analyze data, document results, and assist with literature reviews under supervision. A Bachelor's degree and relevant experience are required; a Master's is preferred.

Qualifications

• Bachelor's degree in a Basic Science or related field; four years of related experience may substitute for degree.
• One year of relevant laboratory experience.

Responsibilities

• Assist in molecular biology techniques and experiments (RT-PCR, RNA/protein isolation, western blotting, cloning, immunofluorescence; biochemical assays).
• Maintain mouse colonies, genotyping by PCR, behavior, breeding, dissections and perfusions.
• Collect, compile and analyze data with postdoctoral associates.
• Conduct literature searches and summarize information for experiments.
• Document results in lab notebook.
• Select, evaluate and apply techniques used in routine research.
• Assist in day-to-day lab activities (buffers, reagents, supplies).
• Train to passage and maintain iPSC cultures and differentiate neuron cultures.

Skills

Data analysis

Literature review

Molecular biology techniques

Mouse handling

Education

Bachelor's degree in Basic Science or related field

Master's degree in basic science or related field

Tools

PCR

Western blotting

Cell culture (iPSC)

Job description

Summary

We are seeking self-motivated individual to work in a laboratory at the Jan and Dan Duncan NRI focused on the underlying genetics and molecular mechanisms of genetic neurological disorders. Candidate will assist in several projects including Alzheimer's Disease, Parkinson's Disease, and MeCP2 projects.

Job Duties

• Assist in molecular biology techniques and experiments including RT-PCR, RNA and protein isolation, western blotting, cloning, and immunofluorescence as well as biochemical assays (GBA and ARSA activity)
• Will maintain mouse colonies, including genotyping the mice via PCR, mouse behavior, setting up breeding cages/weaning pups, dissections and perfusions, sectioning tissue.
• Will collect, compile and analyze data along with postdoctoral associates the candidate will be assisting
• Conduct literature searches and summarizes information in an appropriate format for a particular experiment
• Document results of experiments in lab notebook
• Select, evaluate and apply techniques used in routine research
• Assist in day-to-day lab activities (make buffers, aliquot reagents and order and manage and order general lab supplies)
• Train to passage and maintain induced pluripotent stem cell (iPSC) cultures, and to differentiate and maintain iPSC-derived neuron cultures.
• Perform other job related duties as assigned.

Minimum Qualifications

• Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
• One year of relevant experience.

Preferred Qualifications

• Master's degree in basic science or a related field.
• Experience working with mice is required for this position.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

Requisition ID: 26070

Baylor College of Medicine fosters diversity among its students, trainees, faculty, and staff as a prerequisite to accomplishing our institutional mission and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.