Research Technician III - Genetic Neurological Disorders

Baylor College of Medicine; Texas; On-site; USD 39,000 - 46,000; Full time

Job summary

Baylor College of Medicine in Houston, TX seeks a Research Technician III to advance projects in Genetic Neurological Disorders. The role involves RT-PCR, RNA/protein work, and mouse model handling in a collaborative lab environment within the Division of Molecular and Human Genetics.

Onsite, Mon-Fri, 8-5, salary range $39,150-$46,059; requires a basic science degree and laboratory experience; MS degree and mouse experience are preferred.

Qualifications

• Bachelor's degree in basic science or related field; four years experience may substitute.
• Minimum one year of relevant laboratory experience.
• Experience working with mice is preferred (and may be required).

Responsibilities

• Assist molecular biology techniques and experiments including RT-PCR, RNA/protein isolation, western blotting, cloning, and immunofluorescence.
• Perform biochemical assays such as GBA and ARSA activity.
• Maintain mouse colonies, genotype via PCR, perform mouse behavior studies, and manage breeding.
• Collect, analyze, and summarize data with postdoctoral staff.
• Conduct literature searches and summarize information for experiments.
• Document results in lab notebook and track reagents and supplies.
• Train to passage and maintain iPSC cultures and differentiate neuron cultures.

Skills

RT-PCR

RNA isolation

Protein isolation

Western blotting

Cloning

Immunofluorescence

Biochemical assays

Education

Bachelor's degree in basic science or related field

Master's degree (preferred)

One year of relevant experience

Tools

PCR

iPSC culture

Job description

Research Technician III - Genetic Neurological Disorders

Job Description Job Title: Research Technician III - Genetic Neurological Disorders Division: Molecular and Human Genetics Work Arrangement: Onsite only Location: Houston, TX Salary Range: $39,150 - $46,059 FLSA Status: Nonexempt Work Schedule: Monday – Friday, 8 a.m. – 5 p.m.

Summary

We are seeking self-motivated individual to work in a laboratory at the Jan and Dan Duncan NRI focused on the underlying genetics and molecular mechanisms of genetic neurological disorders. Candidate will assist in several projects including Alzheimer's Disease, Parkinson's Disease, and MeCP2 projects.

Job Duties

• Assist in molecular biology techniques and experiments including RT-PCR, RNA and protein isolation, western blotting, cloning, and immunofluorescence as well as biochemical assays (GBA and ARSA activity)
• Will maintain mouse colonies, including genotyping the mice via PCR, mouse behavior, setting up breeding cages/weaning pups, dissections and perfusions, sectioning tissue.
• Will collect, compile and analyze data along with postdoctoral associates the candidate will be assisting
• Conduct literature searches and summarizes information in an appropriate format for a particular experiment
• Document results of experiments in lab notebook
• Select, evaluate and apply techniques used in routine research
• Assist in day-to-day lab activities (make buffers, aliquot reagents and order and manage and order general lab supplies)
• Train to passage and maintain induced pluripotent stem cell (iPSC) cultures, and to differentiate and maintain iPSC-derived neuron cultures.
• Perform other job related duties as assigned.

Minimum Qualifications

• Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
• One year of relevant experience.

Preferred Qualifications

• Master's degree in basic science or a related field.
• Experience working with mice is required for this position.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

Baylor College of Medicine fosters diversity among its students, trainees, faculty, and staff as a prerequisite to accomplishing our institutional mission and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.